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APC8 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852155

MBS852155 is an antibody targeting APC8. Also known as APC8 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
APC8, Antibody
Full Product Name
APC8 Antibody
Product Gene Name
Product Synonym Names
APC8; Anaphase promoting complex subunit 8; CC23; Cell division cycle protein 23 homolog; Cyclosome subunit 8
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
APC8 antibody detects endogenous levels of total APC8 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
55,882 Da
OMIM
603462
3D Structure
ModBase 3D Structure for Q9UJX2
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human APC8.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-APC8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-APC8 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-APC8 antibody

Western blot analysis of extracts from 293 cells and COS-7 cells, using APC8 antibody.
Anti-APC8 Antibody – Cat# MBS852155

Product References and Citations for anti-APC8 antibody

Oyamatsu T., Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases. Ota T., Nat. Genet. 36:40-45(2004). Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

Other Notes

Small volumes of anti-APC8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for APC8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cell division cycle protein 23 homolog
NCBI Official Synonym Full Names
cell division cycle 23
NCBI Official Symbol
CDC23
NCBI Official Synonym Symbols
APC8; CUT23; ANAPC8
UniProt Protein Name
Cell division cycle protein 23 homolog
UniProt Synonym Protein Names
Anaphase-promoting complex subunit 8; APC8; Cyclosome subunit 8
UniProt Gene Name
CDC23
UniProt Synonym Gene Names
ANAPC8; APC8
NCBI Protein Information
cell division cycle protein 23 homolog

NCBI Summary for APC8

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]
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UniProt Comments for APC8

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-APC8 antibody

 Reference Product  PubMed Publications
 CDC16 antibody  >24 publications with APC8 and CDC16
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