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FMN2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852163

MBS852163 is an antibody targeting FMN2. Also known as FMN2 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FMN2, Antibody
Full Product Name
FMN2 Antibody
Product Gene Name
Product Synonym Names
Formin-2
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
FMN2 antibody detects endogenous levels of total FMN2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
36,871 Da
OMIM
606373
3D Structure
ModBase 3D Structure for Q9NZ56
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human FMN2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-FMN2 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-FMN2 antibody
IHC: 1:50-1:100
ELISA: 1:40000

Immunohistochemistry (IHC) of anti-FMN2 antibody

Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using FMN2 antibody.
Anti-FMN2 Antibody – Cat# MBS852163

Product References and Citations for anti-FMN2 antibody

toki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. Leader B., " Mech. Dev. 93:221-231(2000). Matsuoka S., Science 316:1160-1166(2007).

Other Notes

Small volumes of anti-FMN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FMN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
formin-2 isoform 1
NCBI Official Synonym Full Names
formin 2
NCBI Official Symbol
FMN2
UniProt Protein Name
Formin-2
Protein Family
UniProt Gene Name
FMN2
NCBI Protein Information
formin-2

NCBI Summary for FMN2

This gene is a member of the formin homology protein family. The encoded protein is thought to have essential roles in organization of the actin cytoskeleton and in cell polarity. This protein mediates the formation of an actin mesh that positions the spindle during oogenesis and also regulates the formation of actin filaments in the nucleus. This protein also forms a perinuclear actin/focal-adhesion system that regulates the shape and position of the nucleus during cell migration. Mutations in this gene have been associated with infertility and also with an autosomal recessive form of intellectual disability (MRT47). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2017]
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UniProt Comments for FMN2

Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis (). Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest. Protects cells against apoptosis by protecting CDKN1A against degradation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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