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RAB6A Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852227

MBS852227 is an antibody targeting RAB6A. Also known as RAB6A Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RAB6A, Antibody
Full Product Name
RAB6A Antibody
Product Gene Name
anti-RAB6A antibody
Product Synonym Names
gtp-binding protein rab6c; rab gtpase rab6a; rab6; rab6a; member ras oncogene family; ras-related protein rab6; small gtp binding protein rab6
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
RAB6A antibody detects endogenous levels of total RAB6A protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
19,935 Da
OMIM
179513
3D Structure
ModBase 3D Structure for P20340
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human RAB6A.

Product Categories/Family for anti-RAB6A antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RAB6A antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-RAB6A antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-RAB6A antibody

Western blot analysis of extracts from A549 cells, using RAB6A antibody.
Anti-RAB6A Antibody – Cat# MBS852227

Product References and Citations for anti-RAB6A antibody

Zahraoui A., J. Biol. Chem. 264:12394-12401(1989). Caillol N., J. Cell. Biochem. 79:628-647(2000). Shan J., Gene 257:67-75(2000).

Other Notes

Small volumes of anti-RAB6A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB6A. It may not necessarily be applicable to this product.

NCBI GI #
344030202
NCBI GeneID
5870
NCBI Accession #
NP_001230647.1
UniProt Primary Accession #
P20340
UniProt Secondary Accession #
Q1W5D8; Q5U0A8; Q9UBE4; A8K133; B7Z772; F5H668
UniProt Related Accession #
P20340
GenBank Nucleotide #
NM_001243718.1
NCBI Official Full Name
ras-related protein Rab-6A isoform d
NCBI Official Synonym Full Names
RAB6A, member RAS oncogene family
NCBI Official Symbol
RAB6A
NCBI Official Synonym Symbols
RAB6
UniProt Protein Name
Ras-related protein Rab-6A
Protein Family
Ras-related protein
UniProt Gene Name
RAB6A
UniProt Synonym Gene Names
RAB6; Rab-6
NCBI Protein Information
ras-related protein Rab-6A

NCBI Summary for RAB6A

This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
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UniProt Comments for RAB6A

Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Involved in COPI-independent retrograde transport from the Golgi to the ER (PubMed:25962623).

Research Articles on RAB6A

1. Ectopic expression of an N-terminal-truncated ARHGEF10 mutant led to the generation of large vesicle-like structures containing both Rab6 and Rab8.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB6A antibody

 Reference Product  PubMed Publications
 KIF20A antibody  >3 publications with RAB6A and KIF20A
 BICD2 antibody  >3 publications with RAB6A and BICD2
 BICD1 antibody  >2 publications with RAB6A and BICD1
 TMF1 antibody  >1 publications with RAB6A and TMF1
 SYTL5 antibody  >1 publications with RAB6A and SYTL5
 OCRL antibody  >1 publications with RAB6A and OCRL

Pathways associated with anti-RAB6A antibody

 Products by Pathway  Pathway Diagram
 Pre-NOTCH Expression And Processing Pathway antibodies  Pre-NOTCH Expression And Processing Pathway Diagram
 Pre-NOTCH Processing In Golgi Pathway antibodies  Pre-NOTCH Processing In Golgi Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By NOTCH Pathway antibodies  Signaling By NOTCH Pathway Diagram

Diseases associated with anti-RAB6A antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with RAB6A and Neoplasms
 Brain Diseases Antibodies  >1 publications with RAB6A and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with RAB6A and Kidney Diseases
 Necrosis Antibodies  >1 publications with RAB6A and Necrosis

Organs/Tissues associated with anti-RAB6A antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with RAB6A and Brain
 Kidney Antibodies  >1 publications with RAB6A and Kidney
 Prostate Antibodies  >1 publications with RAB6A and Prostate
 Eye Antibodies  >1 publications with RAB6A and Eye
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