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ARTS-1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852273

MBS852273 is an antibody targeting ARTS-1. Also known as ARTS-1 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARTS-1, Antibody
Full Product Name
ARTS-1 Antibody
Product Gene Name
Product Synonym Names
A-LAP; APPILS; ARTS-1; Adipocyte-derived leucine aminopeptidase precursor; Aminopeptidase PILS; EC 3.4.11.-; PILS-AP; Puromycin-insensitive leucyl-specific aminopeptidase; Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
ARTS-1 antibody detects endogenous levels of total ARTS-1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
107,841 Da
OMIM
606832
3D Structure
ModBase 3D Structure for Q9NZ08
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human ARTS-1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ARTS-1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ARTS-1 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-ARTS-1 antibody

Western blot analysis of extracts from HepG2 cells, Jurkat cells and HUVEC cells, using ARTS-1 antibody.
Anti-ARTS-1 Antibody – Cat# MBS852273

Product References and Citations for anti-ARTS-1 antibody

Hattori A., J. Biochem. 130:235-241(2001). Nakajima D., DNA Res. 9:99-106(2002). Clark H.F., Genome Res. 13:2265-2270(2003).

Other Notes

Small volumes of anti-ARTS-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARTS-1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
endoplasmic reticulum aminopeptidase 1 isoform b
NCBI Official Synonym Full Names
endoplasmic reticulum aminopeptidase 1
NCBI Official Symbol
ERAP1
NCBI Official Synonym Symbols
ALAP; A-LAP; ARTS1; ERAAP; APPILS; ARTS-1; ERAAP1; PILSAP; PILS-AP
UniProt Protein Name
Endoplasmic reticulum aminopeptidase 1
UniProt Synonym Protein Names
ARTS-1; Adipocyte-derived leucine aminopeptidase; A-LAP; Aminopeptidase PILS; Puromycin-insensitive leucyl-specific aminopeptidase; PILS-AP; Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
UniProt Gene Name
ERAP1
UniProt Synonym Gene Names
APPILS; ARTS1; KIAA0525; A-LAP; PILS-AP
NCBI Protein Information
endoplasmic reticulum aminopeptidase 1

NCBI Summary for ARTS-1

The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
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UniProt Comments for ARTS-1

Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ARTS-1 antibody

 Reference Product  PubMed Publications
 TNFRSF1A antibody  >5 publications with ARTS-1 and TNFRSF1A
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