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USP30 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852301

MBS852301 is an antibody targeting USP30. Also known as USP30 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
USP30, Antibody
Full Product Name
USP30 Antibody
Product Gene Name
Product Synonym Names
flj40511; mgc10702; ubiquitin specific peptidase 30; ubiquitin-specific proteinase 30; ubp30; usp30
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
USP30 antibody detects endogenous levels of total USP30 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
58,503 Da
OMIM
612492
3D Structure
ModBase 3D Structure for Q70CQ3
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human USP30.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-USP30 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-USP30 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Testing Data #2 of anti-USP30 antibody

Western blot analysis of extracts from HeLa cells, using USP30 antibody.
Anti-USP30 Antibody – Cat# MBS852301

Product References and Citations for anti-USP30 antibody

Quesada V., Biochem. Biophys. Res. Commun. 314:54-62(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004). Ota T., Nat. Genet. 36:40-45(2004).

Other Notes

Small volumes of anti-USP30 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for USP30. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 30 isoform 2
NCBI Official Synonym Full Names
ubiquitin specific peptidase 30
NCBI Official Symbol
USP30
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 30
UniProt Synonym Protein Names
Deubiquitinating enzyme 30; Ubiquitin thioesterase 30; Ubiquitin-specific-processing protease 30; Ub-specific protease 30
UniProt Gene Name
USP30
UniProt Synonym Gene Names
Ub-specific protease 30
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 30

NCBI Summary for USP30

USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).[supplied by OMIM, Dec 2008]

UniProt Comments for USP30

Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy (PubMed:18287522, PubMed:24896179, PubMed:25527291, PubMed:25621951). Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate to mitophagic signaling (PubMed:25621951). Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65' (PubMed:25527291). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-USP30 antibody

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