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PHACTR4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852367

Rabbit polyclonal PHACTR4 (1) antibody was raised against a recombinate human PHACTR4 protein 139-378aa (BC029266). More details

$430 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PHACTR4, Polyclonal Antibody
Full Product Name
PHACTR4 Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Predicted: Mouse, Rat
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Molecular Weight
7,586 Da
OMIM
608726
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PHACTR4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PHACTR4 antibody
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
IHC: 1:100-1:500

Testing Data of anti-PHACTR4 antibody

Rabbit Anti-PHACTR4 Polyclonal Antibody – Cat# MBS852367

Testing Data of anti-PHACTR4 antibody

Rabbit Anti-PHACTR4 Polyclonal Antibody, Testing Data – Cat# MBS852367

Product References and Citations for anti-PHACTR4 antibody

(1) Beausoleil, S.A., Jedrychowski, M., Schwartz, D., et al. Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004).

Other Notes

Small volumes of anti-PHACTR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PHACTR4 purchase

MBS852367 is an antibody targeting PHACTR4. Also known as PHACTR4 Antibody. Reactive in Human
Predicted: Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PHACTR4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens phosphatase and actin regulator 4, mRNA
NCBI Official Synonym Full Names
phosphatase and actin regulator 4
NCBI Official Symbol
PHACTR4
NCBI Official Synonym Symbols
PPP1R124
UniProt Protein Name
Phosphatase and actin regulator 4
UniProt Gene Name
PHACTR4
NCBI Protein Information
phosphatase and actin regulator 4

NCBI Summary for PHACTR4

This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for PHACTR4

Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin (COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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