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PLEKHG4 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852488

MBS852488 is an antibody targeting PLEKHG4. Also known as PLEKHG4 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLEKHG4, Antibody
Full Product Name
PLEKHG4 Antibody
Product Gene Name
Product Synonym Names
PKHG4; pleckstrin homology domain containing; family G (with RhoGef domain) member 4; pleckstrin homology domain-containing family G member 4; PLEKHG4; PRTPHN1; puratrophin-1; puratrophin1; purkinje cell atrophy-associated protein 1; SCA4
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
PLEKHG4 antibody detects endogenous levels of total PLEKHG4 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
20,247 Da
OMIM
609526
3D Structure
ModBase 3D Structure for Q58EX7
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human PLEKHG4.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PLEKHG4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PLEKHG4 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-PLEKHG4 antibody

Western blot analysis of extracts from K562 cells and COS cells, using PLEKHG4 antibody.
Anti-PLEKHG4 Antibody – Cat# MBS852488

Product References and Citations for anti-PLEKHG4 antibody

Ishikawa K., Am. J. Hum. Genet. 77:280-296(2005). Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-PLEKHG4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLEKHG4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
puratrophin-1 isoform 1
NCBI Official Synonym Full Names
pleckstrin homology and RhoGEF domain containing G4
NCBI Official Symbol
PLEKHG4
NCBI Official Synonym Symbols
SCA4; PRTPHN1; ARHGEF44
UniProt Protein Name
Puratrophin-1
UniProt Synonym Protein Names
Pleckstrin homology domain-containing family G member 4; PH domain-containing family G member 4; Purkinje cell atrophy-associated protein 1
Protein Family
UniProt Gene Name
PLEKHG4
UniProt Synonym Gene Names
PRTPHN1; PH domain-containing family G member 4
NCBI Protein Information
puratrophin-1

NCBI Summary for PLEKHG4

The protein encoded by this gene can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
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UniProt Comments for PLEKHG4

Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi.CautionDefects in PLEKHG4 were initially thought (PubMed:16001362) to be the cause of spinocerebellar ataxia 16q22-linked. However, it was later shown (PubMed:17611710) that it is not the case. Spinocerebellar ataxia 16q22-linked, also known as spinocerebellar ataxia type 31 (SCA31), is caused by defects in BEAN gene.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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