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STEA3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852516

MBS852516 is an antibody targeting STEA3. Also known as STEA3 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
STEA3, Antibody
Full Product Name
STEA3 Antibody
Product Gene Name
Product Synonym Names
Metalloreductase STEAP3; EC 1.16.1.-; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6; pHyde; hpHyde; Dudulin-2; STEAP3; TSAP6
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
STEA3 antibody detects endogenous levels of total STEA3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
50,499 Da
OMIM
609671
3D Structure
ModBase 3D Structure for Q658P3
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human STEA3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-STEA3 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-STEA3 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:10000

Testing Data of anti-STEA3 antibody

Anti-STEA3 Antibody – Cat# MBS852516

Western Blot (WB) of anti-STEA3 antibody

Peptide-+ Western blot analysis of extracts from COLO205 cells, using STEA3 antibody. Immunofluorescence analysis of HeLa cells, using STEA3 antibody.
Anti-STEA3 Antibody, Western Blot (WB) – Cat# MBS852516

Product References and Citations for anti-STEA3 antibody

Passer B.J., Proc. Natl. Acad. Sci. U.S.A. 100:2284-2289(2003). Korkmaz C.G., Oncogene 24:4934-4945(2005). Steiner M.S., Cancer Res. 60:4419-4425(2000).

Other Notes

Small volumes of anti-STEA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STEA3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
metalloreductase STEAP3 isoform b
NCBI Official Synonym Full Names
STEAP3 metalloreductase
NCBI Official Symbol
STEAP3
NCBI Official Synonym Symbols
STMP3; TSAP6; pHyde; AHMIO2; dudlin-2; dudulin-2
UniProt Protein Name
Metalloreductase STEAP3
UniProt Synonym Protein Names
Dudulin-2; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6; pHyde; hpHyde
UniProt Gene Name
STEAP3
UniProt Synonym Gene Names
TSAP6; hTSAP6; hpHyde
NCBI Protein Information
metalloreductase STEAP3

NCBI Summary for STEA3

This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
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UniProt Comments for STEA3

Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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