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DP-1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852532

MBS852532 is an antibody targeting DP-1. Also known as DP-1 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DP-1, Antibody
Full Product Name
DP-1 Antibody
Product Gene Name
Product Synonym Names
E2F DIMERIZATION PARTNER 1; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTOR; SEQUENCE-SPECIFIC; DRTF1; transcription factor Dp-1
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
DP-1 antibody detects endogenous levels of total DP-1 protein.
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
34,921 Da
OMIM
189902
3D Structure
ModBase 3D Structure for Q14186
Immunogen
The antiserum was produced against synthesized peptide derived from human DP-1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DP-1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-DP-1 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:5000

Immunohistochemistry (IHC) of anti-DP-1 antibody

Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using DP-1 antibody.
Anti-DP-1 Antibody – Cat# MBS852532

Western Blot (WB) of anti-DP-1 antibody

Western blot analysis of extracts from HeLa cells, using DP-1 antibody.
Anti-DP-1 Antibody, Western Blot (WB) – Cat# MBS852532

Immunofluorescence (IF) of anti-DP-1 antibody

Forskolin +- Immunofluorescence analysis of HeLa cells, treated with Forskolin (40nM, 30mins), using DP-1 antibody.
Anti-DP-1 Antibody, Immunofluorescence (IF) – Cat# MBS852532

Product References and Citations for anti-DP-1 antibody

K Helin, Genes & Dev., Oct 1993; 7: 1850-1861. B Shan, Cell Growth Differ., Jun 1996; 7: 689. Hironori Ishida, J. Biol. Chem., Jul 2005; 280: 24642-24648. Wing Y. Chang, J. Biol. Chem., Dec 2004; 279: 51343-51353.

Other Notes

Small volumes of anti-DP-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DP-1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transcription factor Dp-1
NCBI Official Synonym Full Names
transcription factor Dp-1
NCBI Official Symbol
TFDP1
NCBI Official Synonym Symbols
DP1; DILC; Dp-1; DRTF1
UniProt Protein Name
Transcription factor Dp-1
UniProt Synonym Protein Names
DRTF1-polypeptide 1; DRTF1; E2F dimerization partner 1
UniProt Gene Name
TFDP1
UniProt Synonym Gene Names
DP1; DRTF1
NCBI Protein Information
transcription factor Dp-1

NCBI Summary for DP-1

This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.[provided by RefSeq, Jan 2009]
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UniProt Comments for DP-1

Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication (PubMed:8405995, PubMed:7739537). The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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