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RASH/RASK/RASN Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852654

MBS852654 is an antibody targeting RASH/RASK/RASN. Also known as RASH/RASK/RASN Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RASH/RASK/RASN, Antibody
Full Product Name
RASH/RASK/RASN Antibody
Product Synonym Names
GTPase NRas; Transforming protein N-Ras; NRAS; HRAS1; GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras; HRAS; HRAS1; GTPase KRas; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras; KRAS; KRAS2; RASK2
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
RASH/RASK/RASN antibody detects endogenous levels of total RASH/RASK/RASN protein.
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
21,229 Da
OMIM
137550
3D Structure
ModBase 3D Structure for P01111
Immunogen
The antiserum was produced against synthesized peptide derived from human RASH/RASK/RASN antibody.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RASH/RASK/RASN antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-RASH/RASK/RASN antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000

Immunohistochemistry (IHC) of anti-RASH/RASK/RASN antibody

Peptide-+ Immunohistochemical analysis of paraffin-embedded human brain tissue using RASH/RASK/RASN antibody.
Anti-RASH/RASK/RASN Antibody – Cat# MBS852654

Western Blot (WB) of anti-RASH/RASK/RASN antibody

Western blot analysis of extracts from HeLa cells, using RASH/RASK/RASN antibody.
Anti-RASH/RASK/RASN Antibody, Western Blot (WB) – Cat# MBS852654

Product References and Citations for anti-RASH/RASK/RASN antibody

Akiyuki Takaya, Mol. Biol. Cell, May 2007; 18: 1850-1860. Waleed F. Khalaf, J. Immunol., Feb 2007; 178: 2527-2534. Izumi Oinuma, J. Biol. Chem., Jan 2007; 282: 303-318. Paul M. Campbell, Cancer Res., Mar 2007; 67: 2098-2106.

Other Notes

Small volumes of anti-RASH/RASK/RASN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RASH/RASK/RASN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GTPase NRas
NCBI Official Synonym Full Names
NRAS proto-oncogene, GTPase
NCBI Official Symbol
NRAS
NCBI Official Synonym Symbols
NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1
UniProt Protein Name
GTPase NRas
UniProt Synonym Protein Names
Transforming protein N-Ras
UniProt Gene Name
NRAS
UniProt Synonym Gene Names
HRAS1
NCBI Protein Information
GTPase NRas

NCBI Summary for RASH/RASK/RASN

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
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UniProt Comments for RASH/RASK/RASN

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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