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PPP1R8 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852729

MBS852729 is an antibody targeting PPP1R8. Also known as PPP1R8 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PPP1R8, Antibody
Full Product Name
PPP1R8 Antibody
Product Gene Name
Product Synonym Names
activator of RNA decay; ARD-1; ARD1; EC 3.1.4.-; NIPP1; nuclear inhibitor of protein phosphatase-1; PP1R8; PPP1R8; PPR8; protein phosphatase 1, regulatory inhibitor subunit 8
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
PPP1R8 antibody detects endogenous levels of total PPP1R8 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
13,344 Da
OMIM
602636
3D Structure
ModBase 3D Structure for Q12972
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human PPP1R8.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PPP1R8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PPP1R8 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-PPP1R8 antibody

Western blot analysis of extracts from Jurkat cells, using PPP1R8 antibody.
Anti-PPP1R8 Antibody – Cat# MBS852729

Product References and Citations for anti-PPP1R8 antibody

Wang M., Proc. Natl. Acad. Sci. U.S.A. 91:10591-10595(1994). Van Eynde A., Eur. J. Biochem. 261:291-300(1999). Liu J.P., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.

Other Notes

Small volumes of anti-PPP1R8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP1R8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nuclear inhibitor of protein phosphatase 1 isoform gamma
NCBI Official Synonym Full Names
protein phosphatase 1 regulatory subunit 8
NCBI Official Symbol
PPP1R8
NCBI Official Synonym Symbols
ARD1; ARD-1; NIPP1; NIPP-1; PRO2047
UniProt Protein Name
Nuclear inhibitor of protein phosphatase 1
UniProt Synonym Protein Names
Protein phosphatase 1 regulatory inhibitor subunit 8Including the following 1 domains:Activator of RNA decay (EC:3.1.4.-)Alternative name(s):ARD-1
UniProt Gene Name
PPP1R8
UniProt Synonym Gene Names
ARD1; NIPP1; NIPP-1
NCBI Protein Information
nuclear inhibitor of protein phosphatase 1

NCBI Summary for PPP1R8

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]
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UniProt Comments for PPP1R8

Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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