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NBL1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852754

MBS852754 is an antibody targeting NBL1. Also known as NBL1 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NBL1, Antibody
Full Product Name
NBL1 Antibody
Product Gene Name
Product Synonym Names
Neuroblastoma suppressor of tumorigenicity 1 [Precursor]; Zinc finger protein DAN; N03; DAN domain family member 1; NBL1; DAN; DAND1
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
NBL1 antibody detects endogenous levels of total NBL1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
23,169 Da
OMIM
600613
3D Structure
ModBase 3D Structure for P41271
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human NBL1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NBL1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-NBL1 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:20000

Testing Data of anti-NBL1 antibody

Peptide-+
Anti-NBL1 Antibody – Cat# MBS852754

Immunohistochemistry (IHC) of anti-NBL1 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using NBL1 antibody. Western blot analysis of extracts from Jurkat cells and COLO cells, using NBL1 antibody.
Anti-NBL1 Antibody, Immunohistochemistry (IHC) – Cat# MBS852754

Immunofluorescence (IF) of anti-NBL1 antibody

Peptide-+ Immunofluorescence analysis of HeLa cells, using NBL1 antibody.
Anti-NBL1 Antibody, Immunofluorescence (IF) – Cat# MBS852754

Product References and Citations for anti-NBL1 antibody

Enomoto H., Oncogene 9:2785-2791(1994). The MGC Project Team, Genome Res. 14:2121-2127(2004). Ahmed A., J. Protein Chem. 20:273-278(2001).

Other Notes

Small volumes of anti-NBL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NBL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neuroblastoma suppressor of tumorigenicity 1 isoform 2
NCBI Official Synonym Full Names
NBL1, DAN family BMP antagonist
NCBI Official Symbol
NBL1
NCBI Official Synonym Symbols
NB; DAN; NO3; DAND1; D1S1733E
UniProt Protein Name
Neuroblastoma suppressor of tumorigenicity 1
UniProt Synonym Protein Names
DAN domain family member 1; Protein N03; Zinc finger protein DAN
UniProt Gene Name
NBL1
UniProt Synonym Gene Names
DAN; DAND1
NCBI Protein Information
neuroblastoma suppressor of tumorigenicity 1

NCBI Summary for NBL1

This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
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UniProt Comments for NBL1

Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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