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ADCK3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852803

MBS852803 is an antibody targeting ADCK3. Also known as ADCK3 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ADCK3, Antibody
Full Product Name
ADCK3 Antibody
Product Gene Name
Product Synonym Names
Chaperone activity of bc1 complex-like,mitochondrial [Precursor]; Chaperone-ABC1-like; aarF domain-containing protein kinase 3; CABC1; ADCK3; PP265
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
ADCK3 antibody detects endogenous levels of total ADCK3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
42,537 Da
OMIM
606980
3D Structure
ModBase 3D Structure for Q8NI60
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human ADCK3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ADCK3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ADCK3 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-ADCK3 antibody

Western blot analysis of extracts from HepG2 cells and mouse muscle cells, using ADCK3 antibody.
Anti-ADCK3 Antibody – Cat# MBS852803

Product References and Citations for anti-ADCK3 antibody

Iiizumi M., Cancer Res. 62:1246-1250(2002). Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004). Gregory S.G., Nature 441:315-321(2006).

Other Notes

Small volumes of anti-ADCK3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ADCK3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
atypical kinase COQ8A, mitochondrial
NCBI Official Synonym Full Names
coenzyme Q8A
NCBI Official Symbol
COQ8A
NCBI Official Synonym Symbols
COQ8; ADCK3; ARCA2; CABC1; SCAR9; COQ10D4
UniProt Protein Name
Atypical kinase COQ8A, mitochondrial
UniProt Synonym Protein Names
Chaperone activity of bc1 complex-like
UniProt Gene Name
COQ8A
UniProt Synonym Gene Names
Chaperone-ABC1-like
NCBI Protein Information
atypical kinase COQ8A, mitochondrial

NCBI Summary for ADCK3

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for ADCK3

Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144, PubMed:21296186, PubMed:25540914, PubMed:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:25498144, PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (PubMed:25498144, PubMed:27499294). Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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