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ARX Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852902

MBS852902 is an antibody targeting ARX. Also known as ARX Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARX, Antibody
Full Product Name
ARX Antibody
Product Gene Name
anti-ARX antibody
Product Synonym Names
aristaless related homeobox; Aristaless-related homeobox; aristaless-related homeobox, X-linked; ARX; Homeobox protein ARX; ISSX; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1; PRTS
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
ARX antibody detects endogenous levels of total ARX protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
58,160 Da
OMIM
300004
3D Structure
ModBase 3D Structure for Q96QS3
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human ARX.

Product Categories/Family for anti-ARX antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ARX antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ARX antibody
WB: 1:500-1:1000
ELISA: 1:1000

Testing Data #2 of anti-ARX antibody

Western blot analysis of extracts from 293 cells, using ARX antibody.
Anti-ARX Antibody – Cat# MBS852902

Product References and Citations for anti-ARX antibody

Ohira R.H., Mol. Genet. Metab. 77:179-188(2002) [PubMed: 12359145]. Turner G., Am. J. Med. Genet. 112:405-411(2002) [PubMed: 12376946]. Bienvenu T., Hum. Mol. Genet. 11:981-991(2002) [PubMed: 11971879].

Other Notes

Small volumes of anti-ARX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARX. It may not necessarily be applicable to this product.

NCBI GI #
24497589
NCBI GeneID
170302
NCBI Accession #
NP_620689.1
UniProt Primary Accession #
Q96QS3
UniProt Related Accession #
Q96QS3
GenBank Nucleotide #
NM_139058.2
NCBI Official Full Name
homeobox protein ARX
NCBI Official Synonym Full Names
aristaless related homeobox
NCBI Official Symbol
ARX
NCBI Official Synonym Symbols
ISSX; PRTS; CT121; EIEE1; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1
UniProt Protein Name
Homeobox protein ARX
UniProt Synonym Protein Names
Aristaless-related homeobox
Protein Family
Aristaless-related homeobox protein
UniProt Gene Name
ARX
NCBI Protein Information
homeobox protein ARX

NCBI Summary for ARX

This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This gene is thought to be involved in CNS development. Expansion of a polyalanine tract and other mutations in this gene cause X-linked cognitive disability and epilepsy. [provided by RefSeq, Jul 2016]
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UniProt Comments for ARX

Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate.

Research Articles on ARX

1. Arx and Dnmt1 that are sufficient for achieving targeted generation of beta cells from adult pancreatic alpha cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ARX antibody

 Disease Name  Pubmed Publications
 Mental Retardation, X-Linked, With Or Without Seizures, Arx-Related Antibodies  >82 publications with ARX and Mental Retardation, X-Linked, With Or Without Seizures, Arx-Related
 Abnormalities, Multiple Antibodies  >24 publications with ARX and Abnormalities, Multiple
 Partington X-linked mental retardation syndrome Antibodies  >14 publications with ARX and Partington X-linked mental retardation syndrome
 Disease Models, Animal Antibodies  >12 publications with ARX and Disease Models, Animal
 Musculoskeletal Diseases Antibodies  >11 publications with ARX and Musculoskeletal Diseases
 Urogenital Abnormalities Antibodies  >6 publications with ARX and Urogenital Abnormalities
 Lissencephaly, X-Linked, 2 Antibodies  >6 publications with ARX and Lissencephaly, X-Linked, 2
 Learning Disorders Antibodies  >5 publications with ARX and Learning Disorders
 Kidney Diseases Antibodies  >3 publications with ARX and Kidney Diseases
 Child Behavior Disorders Antibodies  >3 publications with ARX and Child Behavior Disorders

Organs/Tissues associated with anti-ARX antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >131 publications with ARX and Brain
 Pancreas Antibodies  >44 publications with ARX and Pancreas
 Embryonic Tissue Antibodies  >16 publications with ARX and Embryonic Tissue
 Bone Antibodies  >9 publications with ARX and Bone
 Vascular Antibodies  >8 publications with ARX and Vascular
 Testis Antibodies  >5 publications with ARX and Testis
 Connective Tissue Antibodies  >5 publications with ARX and Connective Tissue
 Skin Antibodies  >3 publications with ARX and Skin
 Lung Antibodies  >1 publications with ARX and Lung
 Uncharacterized Tissue Antibodies  >1 publications with ARX and Uncharacterized Tissue
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