• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CATD Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852960

MBS852960 is an antibody targeting CATD. Also known as CATD (light chain, Cleaved-Gly65) Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CATD, Antibody
Full Product Name
CATD (light chain, Cleaved-Gly65) Antibody
Product Gene Name
Product Synonym Names
Cathepsin D [Precursor]; EC 3.4.23.5; Cathepsin D light chain; Cathepsin D heavy chain; CTSD; CPSD
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CATD (light chain, Cleaved-Gly65) antibody detects endogenous levels of fragment of activated Cathepsin D AND light chain resulting from cleavage adjacent to Gly65.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
44,552 Da
OMIM
116840
3D Structure
ModBase 3D Structure for P07339
Immunogen
The antiserum was produced against synthesized peptide derived from human Cathepsin D AND light chain.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CATD antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CATD antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-CATD antibody

Western blot analysis of extracts from COS-7 cells, treated with etoposide (25uM, 1hour), using CATD (light chain, Cleaved-Gly65) antibody.
Anti-CATD Antibody – Cat# MBS852960

Product References and Citations for anti-CATD antibody

Faust P.L., Proc. Natl. Acad. Sci. U.S.A. 82:4910-4914(1985). Westley B.R., Nucleic Acids Res. 15:3773-3786(1987). Redecker B., DNA Cell Biol. 10:423-431(1991).

Other Notes

Small volumes of anti-CATD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CATD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cathepsin D preproprotein
NCBI Official Synonym Full Names
cathepsin D
NCBI Official Symbol
CTSD
NCBI Official Synonym Symbols
CPSD; CLN10; HEL-S-130P
UniProt Protein Name
Cathepsin D
UniProt Gene Name
CTSD
UniProt Synonym Gene Names
CPSD
NCBI Protein Information
cathepsin D

NCBI Summary for CATD

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
Show more

UniProt Comments for CATD

Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed:27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000