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KCNC1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852980

MBS852980 is an antibody targeting KCNC1. Also known as KCNC1 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KCNC1, Antibody
Full Product Name
KCNC1 Antibody
Product Gene Name
Product Synonym Names
Potassium voltage-gated channel subfamily C member 1; NGK2; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
KCNC1 antibody detects endogenous levels of total KCNC1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
65,871 Da
OMIM
176258
3D Structure
ModBase 3D Structure for P48547
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human KCNC1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KCNC1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-KCNC1 antibody
WB: 1:500-1:1000
ELISA: 1:1000

Western Blot (WB) of anti-KCNC1 antibody

Western blot analysis of extracts from JK cells, using KCNC1 antibody.
Anti-KCNC1 Antibody – Cat# MBS852980

Product References and Citations for anti-KCNC1 antibody

Ried T., Genomics 15:405-411(1993) [PubMed: 8449507]. Grissmer S., J. Biol. Chem. 267:20971-20979(1992) [PubMed: 1400413]. Wang Y., EMBO J. 25:5058-5070(2006) [PubMed: 17053785]. Grissmer S., J. Biol. Chem. 267:20971-20979(1992) [PubMed: 1400413]. Wang Y., EMBO J. 25:5058-5070(2006) [PubMed: 17053785].

Other Notes

Small volumes of anti-KCNC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
potassium voltage-gated channel subfamily C member 1 isoform 1
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily C member 1
NCBI Official Symbol
KCNC1
NCBI Official Synonym Symbols
KV4; EPM7; NGK2; KV3.1
UniProt Protein Name
Potassium voltage-gated channel subfamily C member 1
UniProt Synonym Protein Names
NGK2; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4
UniProt Gene Name
KCNC1
NCBI Protein Information
potassium voltage-gated channel subfamily C member 1

NCBI Summary for KCNC1

This gene encodes a member of a family of integral membrane proteins that mediate the voltage-dependent potassium ion permeability of excitable membranes. Alternative splicing is thought to result in two transcript variants encoding isoforms that differ at their C-termini. These isoforms have had conflicting names in the literature: the longer isoform has been called both "b" and "alpha", while the shorter isoform has been called both "a" and "beta" (PMIDs 1432046, 12091563). [provided by RefSeq, Oct 2014]
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UniProt Comments for KCNC1

Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient (PubMed:25401298). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons.
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Research Articles on KCNC1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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