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BAZ2A Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853206

MBS853206 is an antibody targeting BAZ2A. Also known as BAZ2A Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BAZ2A, Antibody
Full Product Name
BAZ2A Antibody
Product Gene Name
anti-BAZ2A antibody
Product Synonym Names
BA2A; BAZ2A; bromodomain adjacent to zinc finger domain 2A; hWALp3; KIAA0314; TIP5; transcription termination factor-I interacting protein 5; TTF-I interacting protein 5
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
BAZ2A antibody detects endogenous levels of total BAZ2A protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
210,747 Da
OMIM
605682
3D Structure
ModBase 3D Structure for Q9UIF9
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human BAZ2A.

Product Categories/Family for anti-BAZ2A antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-BAZ2A antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-BAZ2A antibody
WB: 1:500~1:1000
ELISA: 1:5000

Western Blot (WB) of anti-BAZ2A antibody

Western blot analysis of extracts from Jurkat cells, using BAZ2A antibody.
Anti-BAZ2A Antibody – Cat# MBS853206

Product References and Citations for anti-BAZ2A antibody

Jones M.H., Genomics 63:40-45(2000). Bechtel S., BMC Genomics 8:399-399(2007). Scherer S.E., Nature 440:346-351(2006).

Other Notes

Small volumes of anti-BAZ2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BAZ2A. It may not necessarily be applicable to this product.

NCBI GI #
91176325
NCBI GeneID
11176
NCBI Accession #
NP_038477.2
UniProt Primary Accession #
Q9UIF9
UniProt Secondary Accession #
O00536; O15030; Q68DI8; Q96H26; B3KN66
UniProt Related Accession #
Q9UIF9
GenBank Nucleotide #
NM_013449.3
NCBI Official Full Name
bromodomain adjacent to zinc finger domain protein 2A isoform 1
NCBI Official Synonym Full Names
bromodomain adjacent to zinc finger domain 2A
NCBI Official Symbol
BAZ2A
NCBI Official Synonym Symbols
TIP5; WALp3
UniProt Protein Name
Bromodomain adjacent to zinc finger domain protein 2A
UniProt Synonym Protein Names
Transcription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3
Protein Family
Bromodomain adjacent to zinc finger domain protein
UniProt Gene Name
BAZ2A
UniProt Synonym Gene Names
KIAA0314; TIP5; TTF-I-interacting protein 5; Tip5
NCBI Protein Information
bromodomain adjacent to zinc finger domain protein 2A

UniProt Comments for BAZ2A

Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing ().
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Research Articles on BAZ2A

1. Data suggest that binding of helical tail of histone 3 (H3) with PHD ('plant homeodomain') fingers of BAZ2A or BAZ2B (bromodomain adjacent to zinc finger domain 2A or 2B) requires molecular recognition of secondary structure motifs within H3 tail and could represent an additional layer of regulation in epigenetic processes.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BAZ2A antibody

 Reference Product  PubMed Publications
 SMARCA5 antibody  >7 publications with BAZ2A and SMARCA5
 TTF1 antibody  >2 publications with BAZ2A and TTF1
 HDAC1 antibody  >2 publications with BAZ2A and HDAC1

Diseases associated with anti-BAZ2A antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with BAZ2A and Neoplasms
 Prostatic Neoplasms Antibodies  >1 publications with BAZ2A and Prostatic Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with BAZ2A and Neoplasms, Experimental
 Genital Diseases, Male Antibodies  >1 publications with BAZ2A and Genital Diseases, Male
 Prostatic Diseases Antibodies  >1 publications with BAZ2A and Prostatic Diseases

Organs/Tissues associated with anti-BAZ2A antibody

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >2 publications with BAZ2A and Prostate
 Bone Antibodies  >1 publications with BAZ2A and Bone
 Kidney Antibodies  >1 publications with BAZ2A and Kidney
 Lymph Antibodies  >1 publications with BAZ2A and Lymph
 Lymph Node Antibodies  >1 publications with BAZ2A and Lymph Node
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