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DUS2L Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853294

MBS853294 is an antibody targeting DUS2L. Also known as DUS2L Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DUS2L, Antibody
Full Product Name
DUS2L Antibody
Product Gene Name
Product Synonym Names
tRNA-dihydrouridine synthase 2-like; EC 1.-.-.-; hDUS2; Up-regulated in lung cancer; URLC8; DUS2L; DUS2
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
DUS2L antibody detects endogenous levels of total DUS2L protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
55,050 Da
OMIM
609707
3D Structure
ModBase 3D Structure for Q9NX74
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human DUS2L.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DUS2L antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-DUS2L antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000

Testing Data of anti-DUS2L antibody

Peptide-+
Anti-DUS2L Antibody – Cat# MBS853294

Immunohistochemistry (IHC) of anti-DUS2L antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle using DUS2L antibody. Western blot analysis of extracts from RAW264.7 cells, using DUS2L antibody.
Anti-DUS2L Antibody, Immunohistochemistry (IHC) – Cat# MBS853294

Product References and Citations for anti-DUS2L antibody

Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004). Kato T., Cancer Res. 65:5638-5646(2005).

Other Notes

Small volumes of anti-DUS2L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DUS2L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tRNA-dihydrouridine(20) synthase
NCBI Official Synonym Full Names
dihydrouridine synthase 2
NCBI Official Symbol
DUS2
NCBI Official Synonym Symbols
SMM1; DUS2L; URLC8
UniProt Protein Name
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
UniProt Synonym Protein Names
Dihydrouridine synthase 2; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2
UniProt Gene Name
DUS2
UniProt Synonym Gene Names
DUS2L; URLC8; hDUS2
NCBI Protein Information
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

NCBI Summary for DUS2L

This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
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UniProt Comments for DUS2L

Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DUS2L antibody

 Reference Product  PubMed Publications
 EPRS antibody  >1 publications with DUS2L and EPRS

Organs/Tissues associated with anti-DUS2L antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with DUS2L and Lung
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