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Claudin 7 (CLDN7) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853404

MBS853404 is an antibody targeting CLDN7. Also known as Claudin 7 (Phospho-Tyr210) Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Claudin 7 (CLDN7), Antibody
Full Product Name
Claudin 7 (Phospho-Tyr210) Antibody
Product Gene Name
Product Synonym Names
CEPTRL2; claudin 7; claudin 9; claudin-1; claudin-7; CLD7; CLDN-7; clostridium perfringens enterotoxin receptor-like 2; CPETRL2
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody againstnon-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificity
Claudin 7 (Phospho-Tyr210) antibody detects endogenous levels of Claudin 7 only when phosphorylated at tyrosine 210.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
16,837 Da
OMIM
609131
3D Structure
ModBase 3D Structure for O95471
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human Claudin 7 around the phosphorylation site of tyrosine 210 (S-K-E-YP-V).
All Sites
Human: Tyr210
Mouse: Tyr210
Rat: Tyr210
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CLDN7 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CLDN7 antibody
WB: 1:500-1:1000
ELISA: 1:1000

Western Blot (WB) of anti-CLDN7 antibody

Western blot analysis of extracts from rat liver cells, using Claudin 7 (Phospho-Tyr210) antibody.
Anti-CLDN7 Antibody – Cat# MBS853404

Product References and Citations for anti-CLDN7 antibody

Keen T.J.; Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases. Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. The MGC Project Team; Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-CLDN7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CLDN7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
claudin-7 isoform 1
NCBI Official Synonym Full Names
claudin 7
NCBI Official Symbol
CLDN7
NCBI Official Synonym Symbols
CLDN-7; CEPTRL2; CPETRL2; Hs.84359; claudin-1
UniProt Protein Name
Claudin-7
Protein Family
UniProt Gene Name
CLDN7
UniProt Synonym Gene Names
CEPTRL2; CPETRL2; CLDN-7
NCBI Protein Information
claudin-7

NCBI Summary for CLDN7

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]
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UniProt Comments for CLDN7

Plays a major role in tight junction-specific obliteration of the intercellular space.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLDN7 antibody

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