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DcR2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853411

Rabbit polyclonal TNFRSF10D(1) antibody was raised against a 15 amino acid peptide from near the intermediate residues of human TNFRSF10D protein. More details

$430 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DcR2, Polyclonal Antibody
Full Product Name
DcR2 Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified by protein A column containing 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Molecular Weight
41,823 Da
OMIM
603614
3D Structure
ModBase 3D Structure for Q9UBN6
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DcR2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-DcR2 antibody
Peptide ELISA: 1:5,000-1:20,000
WB: 1:200-500

Testing Data of anti-DcR2 antibody

Rabbit Anti-DcR2 Polyclonal Antibody – Cat# MBS853411

Product References and Citations for anti-DcR2 antibody

(1) Yang, Q., Kiernan, C.M., Tian, Y., et al. Methylation of CASP8, DCR2, and HIN-1 in neuroblastoma is associated with poor outcome. Clin. Cancer Res. 13 (11), 3191-3197 (2007).

Other Notes

Small volumes of anti-DcR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DcR2 purchase

MBS853411 is an antibody targeting DcR2. Also known as DcR2 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DcR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 10D
NCBI Official Synonym Full Names
TNF receptor superfamily member 10d
NCBI Official Symbol
TNFRSF10D
NCBI Official Synonym Symbols
DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 10D
UniProt Synonym Protein Names
Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL-R4; TRAIL receptor with a truncated death domain; CD_antigen: CD264
Protein Family
UniProt Gene Name
TNFRSF10D
UniProt Synonym Gene Names
DCR2; TRAILR4; TRUNDD; DcR2; TRAIL receptor 4; TRAIL-R4
NCBI Protein Information
tumor necrosis factor receptor superfamily member 10D

NCBI Summary for DcR2

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for DcR2

Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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