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Retinoic Acid Receptor Beta (RAR-beta) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853439

MBS853439 is an antibody targeting RAR-beta. Also known as Retinoic Acid Receptor beta Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Retinoic Acid Receptor beta (RAR-beta), Antibody
Full Product Name
Retinoic Acid Receptor beta Antibody
Product Gene Name
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
Retinoic Acid Receptor beta antibody detects endogenous levels of total Retinoic Acid Receptor beta protein.
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
– Da
OMIM
180220
3D Structure
ModBase 3D Structure for P10826
Immunogen
The antiserum was produced against synthesized peptide derived from human Retinoic Acid Receptor beta.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RAR-beta antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-RAR-beta antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000

Immunohistochemistry (IHC) of anti-RAR-beta antibody

Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Retinoic Acid Receptor beta antibody.
Anti-RAR-beta Antibody – Cat# MBS853439

Western Blot (WB) of anti-RAR-beta antibody

Western blot analysis of extracts from HepG2 cells, using Retinoic Acid Receptor beta antibody.
Anti-RAR-beta Antibody, Western Blot (WB) – Cat# MBS853439

Product References and Citations for anti-RAR-beta antibody

Reuben Lotan, N. Engl. J. Med., May 1995; 332: 1405-1411. Andrew Yen, Mol. Pharmacol., Dec 2004; 66: 1727-1737. K Swisshelm, Cell Growth Differ., Feb 1994; 5: 133. F Aoudjit, Cell Growth Differ., May 1995; 6: 515.

Other Notes

Small volumes of anti-RAR-beta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RAR-beta. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
retinoic acid receptor beta isoform 1
NCBI Official Synonym Full Names
retinoic acid receptor beta
NCBI Official Symbol
RARB
NCBI Official Synonym Symbols
HAP; RRB2; NR1B2; MCOPS12; RARbeta1
UniProt Protein Name
Retinoic acid receptor beta
UniProt Synonym Protein Names
HBV-activated protein; Nuclear receptor subfamily 1 group B member 2; RAR-epsilon
UniProt Gene Name
RARB
UniProt Synonym Gene Names
HAP; NR1B2; RAR-beta
NCBI Protein Information
retinoic acid receptor beta

NCBI Summary for RAR-beta

This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014]
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UniProt Comments for RAR-beta

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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