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TNR16 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853464

MBS853464 is an antibody targeting TNR16. Also known as TNR16 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TNR16, Antibody
Full Product Name
TNR16 Antibody
Product Gene Name
Product Synonym Names
Gp80-LNGFR; NGF receptor; TNFRSF16; TNR16; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; p75 ICD; tumor necrosis factor receptor superfamily member 16
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
TNR16 antibody detects endogenous levels of total TNR16 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
35,767 Da
OMIM
162010
3D Structure
ModBase 3D Structure for P08138
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human TNR16.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TNR16 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-TNR16 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:40000

Testing Data of anti-TNR16 antibody

Anti-TNR16 Antibody – Cat# MBS853464

Western Blot (WB) of anti-TNR16 antibody

Peptide-+ Western blot analysis of extracts from HepG2 cells, using TNR16 antibody. Immunofluorescence analysis of A549 cells, using TNR16 antibody.
Anti-TNR16 Antibody, Western Blot (WB) – Cat# MBS853464

Product References and Citations for anti-TNR16 antibody

Ye X., J. Biol. Chem. 274:30202-30208(1999). Wooten M.W., J. Biol. Chem. 276:7709-7712(2001). Bai D., Biochem. Biophys. Res. Commun. 309:552-557(2003).

Other Notes

Small volumes of anti-TNR16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TNR16. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 16
NCBI Official Synonym Full Names
nerve growth factor receptor
NCBI Official Symbol
NGFR
NCBI Official Synonym Symbols
CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 16
UniProt Synonym Protein Names
Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD_antigen: CD271
UniProt Gene Name
NGFR
UniProt Synonym Gene Names
TNFRSF16; NGF receptor
NCBI Protein Information
tumor necrosis factor receptor superfamily member 16

NCBI Summary for TNR16

Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]
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UniProt Comments for TNR16

Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-TNR16 antibody

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