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eRF3/GSPT1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853501

Rabbit polyclonal eRF3/GSPT1(1) antibody was raised against a 16 amino acid peptide from N terminal residues of human eRF3/GSPT1 protein. More details

$430 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
eRF3/GSPT1, Polyclonal Antibody
Full Product Name
eRF3/GSPT1 Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Purified by peptide affinity column containing 1% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.
Molecular Weight
68,700 Da
OMIM
139259
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-eRF3/GSPT1 antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-eRF3/GSPT1 antibody
Peptide ELISA: 1:5,000-1:20,000
WB: 1:500-1,000
IHC: 1:100-200

Product References and Citations for anti-eRF3/GSPT1 antibody

(1) Malta-Vacas, J., Chauvin, C., Goncalves, L., et al.eRF3a/GSPT1 12-GGC allele increases the susceptibility for breast cancer development.Oncol. Rep. 21 (6), 1551-1558 (2009).

Other Notes

Small volumes of anti-eRF3/GSPT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for eRF3/GSPT1 purchase

MBS853501 is an antibody targeting eRF3/GSPT1. Also known as eRF3/GSPT1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for eRF3/GSPT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform 1
NCBI Official Synonym Full Names
G1 to S phase transition 1
NCBI Official Symbol
GSPT1
NCBI Official Synonym Symbols
GST1; ETF3A; eRF3a; 551G9.2
UniProt Protein Name
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
UniProt Synonym Protein Names
G1 to S phase transition protein 1 homolog
UniProt Gene Name
GSPT1
UniProt Synonym Gene Names
ERF3A; Eukaryotic peptide chain release factor subunit 3a; eRF3a
NCBI Protein Information
eukaryotic peptide chain release factor GTP-binding subunit ERF3A

UniProt Comments for eRF3/GSPT1

Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.CautioneRF3 antibodies used in PubMed:19417104 do not differentiate between GSPT1/ERF3A and GSPT2/ERF3B.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-eRF3/GSPT1 antibody

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