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ATP7B Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853643

MBS853643 is an antibody targeting ATP7B. Also known as ATP7B Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ATP7B, Antibody
Full Product Name
ATP7B Antibody
Product Gene Name
Product Synonym Names
Copper-transporting ATPase 2; EC 3.6.3.4; Copper pump 2; Wilson disease-associated protein; WND/140 kDa; ATP7B; PWD; WC1; WND
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
ATP7B antibody detects endogenous levels of total ATP7B protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
26,021 Da
OMIM
277900
3D Structure
ModBase 3D Structure for P35670
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human ATP7B.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ATP7B antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-ATP7B antibody
IHC: 1:50-1:100
IF: 1:100-1:500
ELISA: 1:1000

Testing Data of anti-ATP7B antibody

Peptide-+
Anti-ATP7B Antibody – Cat# MBS853643

Immunohistochemistry (IHC) of anti-ATP7B antibody

Peptide-+ Immunohistochemistry analysis of paraffin-embedded human testis tissue, using ATP7B antibody. Immunofluorescence analysis of HeLa cells, using ATP7B antibody.
Anti-ATP7B Antibody, Immunohistochemistry (IHC) – Cat# MBS853643

Product References and Citations for anti-ATP7B antibody

Petrukhin K., Hum. Mol. Genet. 3:1647-1656(1994). Dunham A., Nature 428:522-528(2004). Oh W.J., Biochem. Biophys. Res. Commun. 259:206-211(1999).

Other Notes

Small volumes of anti-ATP7B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ATP7B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
copper-transporting ATPase 2 isoform a
NCBI Official Synonym Full Names
ATPase copper transporting beta
NCBI Official Symbol
ATP7B
NCBI Official Synonym Symbols
WD; PWD; WC1; WND
UniProt Protein Name
Copper-transporting ATPase 2
UniProt Synonym Protein Names
Copper pump 2; Wilson disease-associated protein
UniProt Gene Name
ATP7B
UniProt Synonym Gene Names
PWD; WC1; WND
NCBI Protein Information
copper-transporting ATPase 2

NCBI Summary for ATP7B

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008]
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UniProt Comments for ATP7B

Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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