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TAOK3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853669

MBS853669 is an antibody targeting TAOK3. Also known as TAOK3 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TAOK3, Antibody
Full Product Name
TAOK3 Antibody
Product Gene Name
anti-TAOK3 antibody
Product Synonym Names
Serine/threonine-protein kinase TAO3; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; CTCL-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase; Jun kinase-inhibitory kinase; Kinase from chicken homolog A; hKFC-A; Thousand and one amino acid protein 3; TAOK3; DPK; JIK; KDS; MAP3K18
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
TAOK3 antibody detects endogenous levels of total TAOK3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
105,406 Da
OMIM
616711
3D Structure
ModBase 3D Structure for Q9H2K8
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human TAOK3.

Product Categories/Family for anti-TAOK3 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TAOK3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-TAOK3 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Testing Data #2 of anti-TAOK3 antibody

Western blot analysis of extracts from K562 cells, using TAOK3 antibody.
Anti-TAOK3 Antibody – Cat# MBS853669

Product References and Citations for anti-TAOK3 antibody

Tassi E., J. Biol. Chem. 274:33287-33295(1999). Zhang W., Biochem. Biophys. Res. Commun. 274:872-879(2000). Yustein J.T., Oncogene 22:6129-6141(2003).

Other Notes

Small volumes of anti-TAOK3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TAOK3. It may not necessarily be applicable to this product.

NCBI GI #
1080078670
NCBI GeneID
51347
NCBI Accession #
NP_001333417.1
UniProt Primary Accession #
Q9H2K8
UniProt Secondary Accession #
Q658N1; Q8IUM4; Q9HC79; Q9NZM9; Q9UHG7
UniProt Related Accession #
Q9H2K8
GenBank Nucleotide #
NM_001346488.1
NCBI Official Full Name
serine/threonine-protein kinase TAO3 isoform b
NCBI Official Synonym Full Names
TAO kinase 3
NCBI Official Symbol
TAOK3
NCBI Official Synonym Symbols
DPK; JIK; hKFC-A; MAP3K18
UniProt Protein Name
Serine/threonine-protein kinase TAO3
UniProt Synonym Protein Names
Cutaneous T-cell lymphoma-associated antigen HD-CL-09; CTCL-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase; Jun kinase-inhibitory kinase; Kinase from chicken homolog A; hKFC-A; Thousand and one amino acid protein 3
Protein Family
Serine/threonine-protein kinase
UniProt Gene Name
TAOK3
UniProt Synonym Gene Names
DPK; JIK; KDS; MAP3K18; CTCL-associated antigen HD-CL-09; hKFC-A
NCBI Protein Information
serine/threonine-protein kinase TAO3

NCBI Summary for TAOK3

The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases. [provided by RefSeq, Oct 2016]

UniProt Comments for TAOK3

Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).
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Research Articles on TAOK3

1. Results show that three CpG loci within FYN were hypermethylated in obese individuals, while obesity was associated with lower methylation of CpG loci within PIWIL4 and TAOK3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TAOK3 antibody

 Reference Product  PubMed Publications
 TAOK1 antibody  >1 publications with TAOK3 and TAOK1

Pathways associated with anti-TAOK3 antibody

 Products by Pathway  Pathway Diagram
 MAPK (JNK) Signaling Pathway antibodies  MAPK (JNK) Signaling Pathway Diagram
 MAPK (JNK) Signaling Pathway antibodies  MAPK (JNK) Signaling Pathway Diagram
 MAPK (p38) Signaling Pathway antibodies  MAPK (p38) Signaling Pathway Diagram
 MAPK (p38) Signaling Pathway antibodies  MAPK (p38) Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 P38 MAPK Signaling Pathway antibodies  P38 MAPK Signaling Pathway Diagram

Diseases associated with anti-TAOK3 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with TAOK3 and Congenital Abnormalities
 Inflammation Antibodies  >1 publications with TAOK3 and Inflammation

Organs/Tissues associated with anti-TAOK3 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with TAOK3 and Brain
 Prostate Antibodies  >2 publications with TAOK3 and Prostate
 Blood Antibodies  >2 publications with TAOK3 and Blood
 Nerve Antibodies  >1 publications with TAOK3 and Nerve
 Spleen Antibodies  >1 publications with TAOK3 and Spleen
 Heart Antibodies  >1 publications with TAOK3 and Heart
 Lymph Node Antibodies  >1 publications with TAOK3 and Lymph Node
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