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CYB5R3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853680

MBS853680 is an antibody targeting CYB5R3. Also known as CYB5R3 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CYB5R3, Antibody
Full Product Name
CYB5R3 Antibody
Product Gene Name
Product Synonym Names
B5R; cytochrome b5 reductase; cytochrome b5 reductase 3; DIA1; diaphorase; diaphorase (NADH) (cytochrome b-5 reductase); diaphorase-1; EC 1.6.2.2; NADH-cytochrome b5 reductase; NB5R3; NCB5R
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CYB5R3 antibody detects endogenous levels of total CYB5R3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
38,226 Da
OMIM
250800
3D Structure
ModBase 3D Structure for P00387
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CYB5R3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CYB5R3 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CYB5R3 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:40000

Testing Data of anti-CYB5R3 antibody

Peptide-+
Anti-CYB5R3 Antibody – Cat# MBS853680

Immunohistochemistry (IHC) of anti-CYB5R3 antibody

Immunohistochemistry analysis of paraffin-embedded human placenta tissue using CYB5R3 antibody. Western blot analysis of extracts from COLO cells, HUVEC cells, HT-29 cells, K562 cells and HepG2 cells, using CYB5R3 antibody.
Anti-CYB5R3 Antibody, Immunohistochemistry (IHC) – Cat# MBS853680

Product References and Citations for anti-CYB5R3 antibody

Tomatsu S., Gene 80:353-361(1989). Voice M.W.; Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases. Yoon B., Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.

Other Notes

Small volumes of anti-CYB5R3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CYB5R3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
NADH-cytochrome b5 reductase 3 isoform 1
NCBI Official Synonym Full Names
cytochrome b5 reductase 3
NCBI Official Symbol
CYB5R3
NCBI Official Synonym Symbols
B5R; DIA1
UniProt Protein Name
NADH-cytochrome b5 reductase 3
UniProt Synonym Protein Names
Diaphorase-1
UniProt Gene Name
CYB5R3
UniProt Synonym Gene Names
DIA1; B5R; Cytochrome b5 reductase
NCBI Protein Information
NADH-cytochrome b5 reductase 3

NCBI Summary for CYB5R3

This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
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UniProt Comments for CYB5R3

Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CYB5R3 antibody

 Reference Product  PubMed Publications
 CYB5A antibody  >7 publications with CYB5R3 and CYB5A
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