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NCoR1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853834

MBS853834 is an antibody targeting NCoR1. Also known as NCoR1 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NCoR1, Antibody
Full Product Name
NCoR1 Antibody
Product Gene Name
Product Synonym Names
KIAA1047; N-CoR1
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
NCoR1 antibody detects endogenous levels of total NCoR1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
103,919 Da
OMIM
600849
3D Structure
ModBase 3D Structure for O75376
Immunogen
The antiserum was produced against synthesized peptide derived from Internal of human NCoR1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NCoR1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-NCoR1 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000

Testing Data of anti-NCoR1 antibody

Peptide-+
Anti-NCoR1 Antibody – Cat# MBS853834

Immunohistochemistry (IHC) of anti-NCoR1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using NCoR1 antibody. Western blot analysis of extracts from MDA-MB-435 cells, using NCoR1 antibody.
Anti-NCoR1 Antibody, Immunohistochemistry (IHC) – Cat# MBS853834

Product References and Citations for anti-NCoR1 antibody

Igor Girault, Clin. Cancer Res., Apr 2003; 9: 1259. Xinjian Peng, Carcinogenesis, May 2007; 28: 1000-1007. Satoshi Mikawa, Genome Res., May 2007; 17: 586-593. Claire M. Banwell, Clin. Cancer Res., Apr 2006; 12: 2004-2013.

Other Notes

Small volumes of anti-NCoR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NCoR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nuclear receptor corepressor 1 isoform 2
NCBI Official Synonym Full Names
nuclear receptor corepressor 1
NCBI Official Symbol
NCOR1
NCBI Official Synonym Symbols
N-CoR; TRAC1; N-CoR1; hN-CoR; PPP1R109
UniProt Protein Name
Nuclear receptor corepressor 1
UniProt Gene Name
NCOR1
UniProt Synonym Gene Names
KIAA1047; N-CoR; N-CoR1
NCBI Protein Information
nuclear receptor corepressor 1

NCBI Summary for NCoR1

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]
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UniProt Comments for NCoR1

Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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