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TRAF4 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853837

MBS853837 is an antibody targeting TRAF4. Also known as TRAF4 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRAF4, Antibody
Full Product Name
TRAF4 Antibody
Product Gene Name
Product Synonym Names
TNF receptor-associated factor 4; Cysteine-rich domain associated with RING and Traf domains protein 1; Malignant 62; RING finger protein 83; TRAF4; CART1; MLN62; RNF83
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
TRAF4 antibody detects endogenous levels of total TRAF4 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
22,841 Da
OMIM
602464
3D Structure
ModBase 3D Structure for Q9BUZ4
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human TRAF4.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TRAF4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-TRAF4 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Testing Data #2 of anti-TRAF4 antibody

Western blot analysis of extracts from 3T3 cells, using TRAF4 antibody.
Anti-TRAF4 Antibody – Cat# MBS853837

Product References and Citations for anti-TRAF4 antibody

Tomasetto C.L., Genomics 28:367-376(1995). Miller H.G., Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases. Cai C.L., Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.

Other Notes

Small volumes of anti-TRAF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRAF4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TNF receptor-associated factor 4
NCBI Official Synonym Full Names
TNF receptor associated factor 4
NCBI Official Symbol
TRAF4
NCBI Official Synonym Symbols
CART1; MLN62; RNF83
UniProt Protein Name
TNF receptor-associated factor 4
UniProt Synonym Protein Names
Cysteine-rich domain associated with RING and Traf domains protein 1; Metastatic lymph node gene 62 protein; MLN 62; RING finger protein 83
UniProt Gene Name
TRAF4
UniProt Synonym Gene Names
CART1; MLN62; RNF83; MLN 62
NCBI Protein Information
TNF receptor-associated factor 4

NCBI Summary for TRAF4

This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for TRAF4

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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