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Nuclear Protein 1 (NUPR1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854009

Purified mouse monoclonal antibody generated using E Coli expressed recombinant protein Nuclear protein 1 as immunogen. More details

$455 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nuclear protein 1 (NUPR1), Monoclonal Antibody
Full Product Name
Nuclear protein 1 Antibody
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b
Host
Mouse
Form/Format
Each vial contains 100 ug IgG in 100 ul of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
Specificity
Anti-Nuclear protein 1 recognizes recombinant protein Nuclear protein 1.
Preparation and Storage
The antibody may be stored at-20 degree C for one year in its original formulation. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.
Molecular Weight
10,691 Da
OMIM
614812
3D Structure
ModBase 3D Structure for O60356
Immunogen
Recombinant protein corresponding to full length Nuclear protein 1.

Product Categories/Family for anti-NUPR1 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Testing Data of anti-NUPR1 antibody

Mouse Anti-NUPR1 Monoclonal Antibody – Cat# MBS854009

Other Notes

Small volumes of anti-NUPR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NUPR1 purchase

MBS854009 is an antibody targeting NUPR1. Also known as Nuclear protein 1 Antibody. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for NUPR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nuclear protein 1 isoform b
NCBI Official Synonym Full Names
nuclear protein 1, transcriptional regulator
NCBI Official Symbol
NUPR1
NCBI Official Synonym Symbols
P8; COM1
UniProt Protein Name
Nuclear protein 1
UniProt Synonym Protein Names
Candidate of metastasis 1; Nuclear transcriptional regulator protein 1
Protein Family
UniProt Gene Name
NUPR1
NCBI Protein Information
nuclear protein 1

UniProt Comments for NUPR1

Chromatin-binding protein that converts stress signals into a program of gene expression that empowers cells with resistance to the stress induced by a change in their microenvironment. Interacts with MSL1 and inhibits its activity on histone H4 'Lys-16' acetylation (H4K16ac). Binds the RELB promoter and activates its transcription, leading to the transactivation of IER3. The NUPR1/RELB/IER3 survival pathway may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment. In breast cancer cells, NUPR1 overexpression leads to the activation of PI3K/AKT signaling pathway, CDKN1A/p21 phosphorylation and relocalization from the nucleus to the cytoplasm, leading to resistance to chemotherapeutic agents, such as doxorubicin.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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