• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

NEIL1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854148

MBS854148 is an antibody targeting NEIL1. Also known as NEIL1 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NEIL1, Antibody
Full Product Name
NEIL1 Antibody
Product Gene Name
Product Synonym Names
DNA glycosylase/ap lyase neil1; DNA-(apurinic or apyrimidinic site) lyase neil1; endonuclease viii; endonuclease viii-like 1; fpg1; hfpg1; neh1; nei endonuclease viii-like 1; nei-like 1; nei1; neil1
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
NEIL1 antibody detects endogenous levels of total NEIL1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
43,684 Da
OMIM
608844
3D Structure
ModBase 3D Structure for Q96FI4
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human NEIL1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NEIL1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-NEIL1 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-NEIL1 antibody

Western blot analysis of extracts from HeLa cells, using NEIL1 antibody.
Anti-NEIL1 Antibody – Cat# MBS854148

Product References and Citations for anti-NEIL1 antibody

Takao M., J. Biol. Chem. 277:42205-42213(2002). Ota T., Nat. Genet. 36:40-45(2004). Bandaru V., DNA Repair 1:517-529(2002).

Other Notes

Small volumes of anti-NEIL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NEIL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
endonuclease 8-like 1 isoform 1
NCBI Official Synonym Full Names
nei like DNA glycosylase 1
NCBI Official Symbol
NEIL1
NCBI Official Synonym Symbols
FPG1; NEI1; hFPG1
UniProt Protein Name
Endonuclease 8-like 1
UniProt Synonym Protein Names
DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; Endonuclease VIII-like 1; FPG1; Nei homolog 1; NEH1; Nei-like protein 1
Protein Family
UniProt Gene Name
NEIL1
UniProt Synonym Gene Names
NEH1
NCBI Protein Information
endonuclease 8-like 1

NCBI Summary for NEIL1

This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Show more

UniProt Comments for NEIL1

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Has DNA glycosylase/lyase activity towards mismatched uracil and thymine, in particular in U:C and T:C mismatches. Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NEIL1 antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000