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CEP135 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854264

MBS854264 is an antibody targeting CEP135. Also known as CEP135 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CEP135, Antibody
Full Product Name
CEP135 Antibody
Product Gene Name
anti-CEP135 antibody
Product Synonym Names
centrosomal protein 4; Cep135; CP135; KIAA0635
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CEP135 antibody detects endogenous levels of total CEP135 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
28,910 Da
OMIM
611423
3D Structure
ModBase 3D Structure for Q66GS9
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human CEP135.

Product Categories/Family for anti-CEP135 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CEP135 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CEP135 antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-CEP135 antibody

Western blot analysis of extracts from COLO cells, using CEP135 antibody.
Anti-CEP135 Antibody – Cat# MBS854264

Product References and Citations for anti-CEP135 antibody

Ishikawa K., DNA Res. 5:169-176(1998). Ota T., Nat. Genet. 36:40-45(2004). Andersen J.S., Nature 426:570-574(2003).

Other Notes

Small volumes of anti-CEP135 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CEP135. It may not necessarily be applicable to this product.

NCBI GI #
50083279
NCBI GeneID
9662
NCBI Accession #
NP_079285.2
UniProt Primary Accession #
Q66GS9
UniProt Secondary Accession #
O75130; Q58F25; Q9H8H7; B2RMY0
UniProt Related Accession #
Q66GS9
GenBank Nucleotide #
NM_025009.4
NCBI Official Full Name
centrosomal protein of 135 kDa
NCBI Official Synonym Full Names
centrosomal protein 135
NCBI Official Symbol
CEP135
NCBI Official Synonym Symbols
CEP4; MCPH8; KIAA0635
UniProt Protein Name
Centrosomal protein of 135 kDa
UniProt Synonym Protein Names
Centrosomal protein 4
Protein Family
Centrosomal protein
UniProt Gene Name
CEP135
UniProt Synonym Gene Names
CEP4; KIAA0635; Cep135
NCBI Protein Information
centrosomal protein of 135 kDa

NCBI Summary for CEP135

This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8. [provided by RefSeq, Jun 2012]
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UniProt Comments for CEP135

Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP and CEP290 and recruitment of WRAP73 to centrioles. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole.
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Research Articles on CEP135

1. CEP135 segment 96-108 is a major microtubule-binding site.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CEP135 antibody

 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Centrosome Maturation Pathway antibodies  Centrosome Maturation Pathway Diagram
 G2/M Transition Pathway antibodies  G2/M Transition Pathway Diagram
 Loss Of Nlp From Mitotic Centrosomes Pathway antibodies  Loss Of Nlp From Mitotic Centrosomes Pathway Diagram
 Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway antibodies  Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway Diagram
 Mitotic G2-G2/M Phases Pathway antibodies  Mitotic G2-G2/M Phases Pathway Diagram
 Recruitment Of Mitotic Centrosome Proteins And Complexes Pathway antibodies  Recruitment Of Mitotic Centrosome Proteins And Complexes Pathway Diagram

Diseases associated with anti-CEP135 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with CEP135 and Congenital Abnormalities
 Intestinal Neoplasms Antibodies  >1 publications with CEP135 and Intestinal Neoplasms
 Nervous System Malformations Antibodies  >1 publications with CEP135 and Nervous System Malformations
 Neoplasms Antibodies  >1 publications with CEP135 and Neoplasms

Organs/Tissues associated with anti-CEP135 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with CEP135 and Brain
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