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Collagen V Alpha3 (CO5A3) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854353

MBS854353 is an antibody targeting CO5A3. Also known as Collagen V alpha3 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Collagen V alpha3 (CO5A3), Antibody
Full Product Name
Collagen V alpha3 Antibody
Product Gene Name
anti-CO5A3 antibody
Product Synonym Names
collagen alpha 3
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
Collagen V alpha3 antibody detects endogenous levels of total Collagen V alpha3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
172,121 Da
OMIM
120216
3D Structure
ModBase 3D Structure for P25940
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human Collagen V alpha3.

Product Categories/Family for anti-CO5A3 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CO5A3 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-CO5A3 antibody
IHC: 1:50-1:100
IF: 1:100-1:500
ELISA: 1:40000

Testing Data of anti-CO5A3 antibody

Peptide-+
Anti-CO5A3 Antibody – Cat# MBS854353

Immunohistochemistry (IHC) of anti-CO5A3 antibody

Peptide-+ Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Collagen V alpha3 antibody. Immunofluorescence analysis of HeLa cells, using Collagen V alpha3 antibody.
Anti-CO5A3 Antibody, Immunohistochemistry (IHC) – Cat# MBS854353

Product References and Citations for anti-CO5A3 antibody

Imamura Y., J. Biol. Chem. 275:8749-8759(2000). Mann K., Biol. Chem. Hoppe-Seyler 373:69-75(1992). Molina H., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).

Other Notes

Small volumes of anti-CO5A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CO5A3. It may not necessarily be applicable to this product.

NCBI GI #
110735435
NCBI GeneID
50509
NCBI Accession #
NP_056534.2
UniProt Primary Accession #
P25940
UniProt Secondary Accession #
Q9NZQ6
UniProt Related Accession #
P25940
GenBank Nucleotide #
NM_015719.3
NCBI Official Full Name
collagen alpha-3(V) chain preproprotein
NCBI Official Synonym Full Names
collagen type V alpha 3 chain
NCBI Official Symbol
COL5A3
UniProt Protein Name
Collagen alpha-3(V) chain
UniProt Gene Name
COL5A3
NCBI Protein Information
collagen alpha-3(V) chain

NCBI Summary for CO5A3

This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages. [provided by RefSeq, Jul 2008]
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UniProt Comments for CO5A3

Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.

Research Articles on CO5A3

1. Absence of obvious disease-causing mutations and null alleles in a cohort of 13 patients with h-EDS is consistent with exclusion of COL5A3 as a candidate gene for this disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CO5A3 antibody

 Reference Product  PubMed Publications
 COL5A1 antibody  >4 publications with CO5A3 and COL5A1
 COL1A2 antibody  >1 publications with CO5A3 and COL1A2

Pathways associated with anti-CO5A3 antibody

 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram

Diseases associated with anti-CO5A3 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >4 publications with CO5A3 and Cardiovascular Diseases
 Hypertension Antibodies  >2 publications with CO5A3 and Hypertension
 Fibrosis Antibodies  >2 publications with CO5A3 and Fibrosis
 Pain Antibodies  >1 publications with CO5A3 and Pain
 Disease Models, Animal Antibodies  >1 publications with CO5A3 and Disease Models, Animal
 Weight Gain Antibodies  >1 publications with CO5A3 and Weight Gain

Organs/Tissues associated with anti-CO5A3 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >4 publications with CO5A3 and Bone
 Skin Antibodies  >4 publications with CO5A3 and Skin
 Connective Tissue Antibodies  >3 publications with CO5A3 and Connective Tissue
 Eye Antibodies  >1 publications with CO5A3 and Eye
 Placenta Antibodies  >1 publications with CO5A3 and Placenta
 Kidney Antibodies  >1 publications with CO5A3 and Kidney
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