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CYSLTR1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854471

MBS854471 is an antibody targeting CYSLTR1. Also known as CYSLTR1 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CYSLTR1, Antibody
Full Product Name
CYSLTR1 Antibody
Product Gene Name
Product Synonym Names
CLTR1; CYSLT1; CYSLT1R; CYSLTR; cysteinyl leukotriene D4 receptor; cysteinyl leukotriene receptor 1; HG55; HMTMF81; LTD4 receptorCLTR1; CYSLT1; CYSLT1R; CYSLTR; cysteinyl leukotriene D4 receptor; cysteinyl leukotriene receptor 1; HG55; HMTMF81; LTD4 receptor
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CYSLTR1 antibody detects endogenous levels of total CYSLTR1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
38,541 Da
OMIM
300201
3D Structure
ModBase 3D Structure for Q9Y271
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CYSLTR1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CYSLTR1 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-CYSLTR1 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:5000

Testing Data of anti-CYSLTR1 antibody

Anti-CYSLTR1 Antibody – Cat# MBS854471

Western Blot (WB) of anti-CYSLTR1 antibody

Peptide-+ Western blot analysis of extracts from HeLa cells, HT-29 cells and COLO205 cells, using CYSLTR1 antibody. Immunofluorescence analysis of COS-7 cells, using CYSLTR1 antibody.
Anti-CYSLTR1 Antibody, Western Blot (WB) – Cat# MBS854471

Product References and Citations for anti-CYSLTR1 antibody

Lynch K.R., Nature 399:789-793(1999). Sarau H.M., Mol. Pharmacol. 56:657-663(1999). Ross M.T., Nature 434:325-337(2005).

Other Notes

Small volumes of anti-CYSLTR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CYSLTR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cysteinyl leukotriene receptor 1
NCBI Official Synonym Full Names
cysteinyl leukotriene receptor 1
NCBI Official Symbol
CYSLTR1
NCBI Official Synonym Symbols
CYSLT1; CYSLTR; CYSLT1R; HMTMF81
UniProt Protein Name
Cysteinyl leukotriene receptor 1
UniProt Synonym Protein Names
Cysteinyl leukotriene D4 receptor; LTD4 receptor; G-protein coupled receptor HG55; HMTMF81
UniProt Gene Name
CYSLTR1
UniProt Synonym Gene Names
CYSLT1; CysLTR1; LTD4 receptor
NCBI Protein Information
cysteinyl leukotriene receptor 1

NCBI Summary for CYSLTR1

This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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UniProt Comments for CYSLTR1

Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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