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SENP5 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854515

MBS854515 is an antibody targeting SENP5. Also known as SENP5 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SENP5, Antibody
Full Product Name
SENP5 Antibody
Product Gene Name
Product Synonym Names
EC 3.4.22.-; SUMO1/sentrin specific peptidase 5
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
SENP5 antibody detects endogenous levels of total SENP5 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
81,310 Da
OMIM
612845
3D Structure
ModBase 3D Structure for Q96HI0
Immunogen
The antiserum was produced against synthesized peptide derived from Internal of human SENP5.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SENP5 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-SENP5 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000

Testing Data of anti-SENP5 antibody

Peptide-+
Anti-SENP5 Antibody – Cat# MBS854515

Immunohistochemistry (IHC) of anti-SENP5 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using SENP5 antibody. Western blot analysis of extracts from COS7 cells, using SENP5 antibody.
Anti-SENP5 Antibody, Immunohistochemistry (IHC) – Cat# MBS854515

Product References and Citations for anti-SENP5 antibody

Alessandra Di Bacco, Mol. Cell. Biol., Jun 2006; 26: 4489-4498. Thomas Colby, Plant Physiology, Sep 2006; 142: 318-332. Pei-Zheng Zheng, PNAS, May 2005; 102: 7653-7658. Rodolfo Zunino, J. Cell Sci., Apr 2007; 120: 1178-1188.

Other Notes

Small volumes of anti-SENP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SENP5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sentrin-specific protease 5 isoform 2
NCBI Official Synonym Full Names
SUMO specific peptidase 5
NCBI Official Symbol
SENP5
UniProt Protein Name
Sentrin-specific protease 5
UniProt Synonym Protein Names
Sentrin/SUMO-specific protease SENP5
UniProt Gene Name
SENP5
NCBI Protein Information
sentrin-specific protease 5

NCBI Summary for SENP5

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]
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UniProt Comments for SENP5

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SENP5 antibody

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