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NAB2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854525

MBS854525 is an antibody targeting NAB2. Also known as NAB2 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NAB2, Antibody
Full Product Name
NAB2 Antibody
Product Gene Name
Product Synonym Names
EGR-1-binding protein 2; MADER; Melanoma-associated delayed early response protein; NGFI-A-binding protein 2
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
NAB2 antibody detects endogenous levels of total NAB2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
49,748 Da
OMIM
602381
3D Structure
ModBase 3D Structure for Q15742
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human NAB2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NAB2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-NAB2 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000

Testing Data of anti-NAB2 antibody

Peptide-+
Anti-NAB2 Antibody – Cat# MBS854525

Immunohistochemistry (IHC) of anti-NAB2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using NAB2 antibody. Western blot analysis of extracts from HT-29 cells and RAW264.7 cells, using NAB2 antibody.
Anti-NAB2 Antibody, Immunohistochemistry (IHC) – Cat# MBS854525

Product References and Citations for anti-NAB2 antibody

Svaren J., Mol. Cell. Biol. 16:3545-3553(1996). Kirsch K.H., Oncogene 12:963-971(1996). Svaren J., Genomics 41:33-39(1997).

Other Notes

Small volumes of anti-NAB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NAB2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
NGFI-A-binding protein 2 isoform 2
NCBI Official Synonym Full Names
NGFI-A binding protein 2
NCBI Official Symbol
NAB2
NCBI Official Synonym Symbols
MADER
UniProt Protein Name
NGFI-A-binding protein 2
UniProt Synonym Protein Names
EGR-1-binding protein 2; Melanoma-associated delayed early response protein; Protein MADER
UniProt Gene Name
NAB2
UniProt Synonym Gene Names
MADER; Protein MADER
NCBI Protein Information
NGFI-A-binding protein 2

NCBI Summary for NAB2

This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for NAB2

Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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