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EMR3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854564

MBS854564 is an antibody targeting EMR3. Also known as EMR3 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EMR3, Antibody
Full Product Name
EMR3 Antibody
Product Gene Name
anti-EMR3 antibody
Product Synonym Names
EGF-like module-containing mucin-like hormone receptor-like 3 [Precursor]; EGF-like module-containing mucin-like hormone receptor-like 3 [Precursor]; EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha; EGF-like module-containing mucin-like hormone receptor-like 3 subunit beta; EMR3; UNQ683/PRO1562
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
EMR3 antibody detects endogenous levels of total EMR3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
12,703 Da
OMIM
606101
3D Structure
ModBase 3D Structure for Q9BY15
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human EMR3.

Product Categories/Family for anti-EMR3 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-EMR3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-EMR3 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-EMR3 antibody

Western blot analysis of extracts from Jurkat cells, using EMR3 antibody.
Anti-EMR3 Antibody – Cat# MBS854564

Product References and Citations for anti-EMR3 antibody

Stacey M., J. Biol. Chem. 276:18863-18870(2001). Clark H.F., Genome Res. 13:2265-2270(2003). Olsen J.V., Cell 127:635-648(2006).

Other Notes

Small volumes of anti-EMR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EMR3. It may not necessarily be applicable to this product.

NCBI GI #
574584843
NCBI GeneID
84658
NCBI Accession #
NP_001276087.1
UniProt Primary Accession #
Q9BY15
UniProt Related Accession #
Q9BY15
GenBank Nucleotide #
NM_001289158.1
NCBI Official Full Name
adhesion G protein-coupled receptor E3 isoform 2
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor E3
NCBI Official Symbol
ADGRE3
NCBI Official Synonym Symbols
EMR3
UniProt Protein Name
Adhesion G protein-coupled receptor E3
UniProt Synonym Protein Names
EGF-like module receptor 3; EGF-like module-containing mucin-like hormone receptor-like 3
UniProt Gene Name
ADGRE3
NCBI Protein Information
adhesion G protein-coupled receptor E3

NCBI Summary for EMR3

This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]
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UniProt Comments for EMR3

Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes-derived macrophages and activated neutrophils.

Research Articles on EMR3

1. Given the poor survival associated with high levels of EMR-3 expression in glioma patients, impetus is provided to explore EMR-3 as a potential therapeutic target.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-EMR3 antibody

 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with anti-EMR3 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >5 publications with EMR3 and Inflammation
 Immune System Diseases Antibodies  >3 publications with EMR3 and Immune System Diseases
 Cardiovascular Diseases Antibodies  >1 publications with EMR3 and Cardiovascular Diseases
 Neoplasm Invasiveness Antibodies  >1 publications with EMR3 and Neoplasm Invasiveness
 Pneumonia Antibodies  >1 publications with EMR3 and Pneumonia
 Esophageal Neoplasms Antibodies  >1 publications with EMR3 and Esophageal Neoplasms
 Atherosclerosis Antibodies  >1 publications with EMR3 and Atherosclerosis
 Carcinoma, Squamous Cell Antibodies  >1 publications with EMR3 and Carcinoma, Squamous Cell
 Breast Neoplasms Antibodies  >1 publications with EMR3 and Breast Neoplasms

Organs/Tissues associated with anti-EMR3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with EMR3 and Blood
 Spleen Antibodies  >1 publications with EMR3 and Spleen
 Lung Antibodies  >1 publications with EMR3 and Lung
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