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MTERF Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854619

MBS854619 is an antibody targeting MTERF. Also known as MTERF Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MTERF, Antibody
Full Product Name
MTERF Antibody
Product Gene Name
anti-MTERF antibody
Product Synonym Names
MGC131634; mitochondrial transcription termination factor 1
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
MTERF antibody detects endogenous levels of total MTERF protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
45,778 Da
OMIM
602318
3D Structure
ModBase 3D Structure for Q99551
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human MTERF.

Product Categories/Family for anti-MTERF antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MTERF antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-MTERF antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000

Testing Data #3 of anti-MTERF antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using MTERF antibody.
Western blot analysis of extracts from Jurkat cells, using MTERF antibody.
Anti-MTERF Antibody – Cat# MBS854619

Product References and Citations for anti-MTERF antibody

Fernandez-Silva P., EMBO J. 16:1066-1079(1997). Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. Hillier L.W., Nature 424:157-164(2003).

Other Notes

Small volumes of anti-MTERF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MTERF. It may not necessarily be applicable to this product.

NCBI GI #
667477562
NCBI GeneID
7978
NCBI Accession #
NP_001288063.1
UniProt Primary Accession #
Q99551
UniProt Secondary Accession #
Q32NF8; Q53H51; Q9BVR7; A4D1E3
UniProt Related Accession #
Q99551
GenBank Nucleotide #
NM_001301134.1
NCBI Official Full Name
transcription termination factor 1, mitochondrial isoform 2
NCBI Official Synonym Full Names
mitochondrial transcription termination factor 1
NCBI Official Symbol
MTERF1
NCBI Official Synonym Symbols
MTERF
UniProt Protein Name
Transcription termination factor 1, mitochondrial
UniProt Synonym Protein Names
Mitochondrial transcription termination factor 1; mTERF; mTERF1
Protein Family
Transcription termination factor
UniProt Gene Name
MTERF1
UniProt Synonym Gene Names
MTERF; mTERF; mTERF1
NCBI Protein Information
transcription termination factor 1, mitochondrial

NCBI Summary for MTERF

This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding. [provided by RefSeq, Jul 2008]
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UniProt Comments for MTERF

Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand.
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Research Articles on MTERF

1. MTERF1 has the ability to accommodate alternate active conformations.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MTERF antibody

 Reference Product  PubMed Publications
 TFAM antibody  >2 publications with MTERF and TFAM
 POLRMT antibody  >1 publications with MTERF and POLRMT
 MPV17 antibody  >1 publications with MTERF and MPV17

Pathways associated with anti-MTERF antibody

 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Mitochondrial Biogenesis Pathway antibodies  Mitochondrial Biogenesis Pathway Diagram
 Mitochondrial Transcription Termination Pathway antibodies  Mitochondrial Transcription Termination Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies  RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
 Transcription From Mitochondrial Promoters Pathway antibodies  Transcription From Mitochondrial Promoters Pathway Diagram
 Transcriptional Activation Of Mitochondrial Biogenesis Pathway antibodies  Transcriptional Activation Of Mitochondrial Biogenesis Pathway Diagram

Diseases associated with anti-MTERF antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >1 publications with MTERF and Kidney Diseases
 Necrosis Antibodies  >1 publications with MTERF and Necrosis

Organs/Tissues associated with anti-MTERF antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with MTERF and Liver
 Muscle Antibodies  >1 publications with MTERF and Muscle
 Skin Antibodies  >1 publications with MTERF and Skin
 Embryonic Tissue Antibodies  >1 publications with MTERF and Embryonic Tissue
 Kidney Antibodies  >1 publications with MTERF and Kidney
 Brain Antibodies  >1 publications with MTERF and Brain
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