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JIP3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854623

MBS854623 is an antibody targeting JIP3. Also known as JIP3 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
JIP3, Antibody
Full Product Name
JIP3 Antibody
Product Gene Name
Product Synonym Names
C-jun-amino-terminal kinase interacting protein 3; JIP-3; JIP3; JNK MAP kinase scaffold protein 3; JNK-interacting protein 3; JNK/SAPK-associated protein 1; JSAP1; KIAA1066; MAPK8IP3; Mitogen-activated protein kinase 8-interacting protein 3; SYD2; Sunday driver 2
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
JIP3 antibody detects endogenous levels of total JIP3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
29,052 Da
OMIM
605431
3D Structure
ModBase 3D Structure for Q9UPT6
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human JIP3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-JIP3 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-JIP3 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:20000

Testing Data of anti-JIP3 antibody

Anti-JIP3 Antibody – Cat# MBS854623

Western Blot (WB) of anti-JIP3 antibody

Peptide-+ Western blot analysis of extracts from HeLa cells, using JIP3 antibody. Immunofluorescence analysis of HeLa cells, using JIP3 antibody.
Anti-JIP3 Antibody, Western Blot (WB) – Cat# MBS854623

Product References and Citations for anti-JIP3 antibody

Hattori A., DNA Res. 7:357-366(2000). Martin J., Nature 432:988-994(2004). Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).

Other Notes

Small volumes of anti-JIP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for JIP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-Jun-amino-terminal kinase-interacting protein 3 isoform 2
NCBI Official Synonym Full Names
mitogen-activated protein kinase 8 interacting protein 3
NCBI Official Symbol
MAPK8IP3
NCBI Official Synonym Symbols
syd; JIP3; SYD2; JIP-3; JSAP1
UniProt Protein Name
C-Jun-amino-terminal kinase-interacting protein 3
UniProt Synonym Protein Names
JNK MAP kinase scaffold protein 3; Mitogen-activated protein kinase 8-interacting protein 3
UniProt Gene Name
MAPK8IP3
UniProt Synonym Gene Names
JIP3; KIAA1066; JIP-3; JNK-interacting protein 3
NCBI Protein Information
C-Jun-amino-terminal kinase-interacting protein 3

NCBI Summary for JIP3

The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for JIP3

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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