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RFX2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854656

MBS854656 is an antibody targeting RFX2. Also known as RFX2 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RFX2, Antibody
Full Product Name
RFX2 Antibody
Product Gene Name
Product Synonym Names
DNA-binding protein RFX2; Regulatory factor X 2
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
RFX2 antibody detects endogenous levels of total RFX2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
77,268 Da
OMIM
142765
3D Structure
ModBase 3D Structure for P48378
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human RFX2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RFX2 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-RFX2 antibody
IHC: 1:50-1:100
ELISA: 1:10000

Immunohistochemistry (IHC) of anti-RFX2 antibody

Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using RFX2 antibody.
Anti-RFX2 Antibody – Cat# MBS854656

Product References and Citations for anti-RFX2 antibody

Reith W., Mol. Cell. Biol. 14:1230-1244(1994). Sjoeblom T., Science 314:268-274(2006).

Other Notes

Small volumes of anti-RFX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RFX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DNA-binding protein RFX2 isoform a
NCBI Official Synonym Full Names
regulatory factor X2
NCBI Official Symbol
RFX2
UniProt Protein Name
DNA-binding protein RFX2
UniProt Synonym Protein Names
Regulatory factor X 2
Protein Family
UniProt Gene Name
RFX2
NCBI Protein Information
DNA-binding protein RFX2

NCBI Summary for RFX2

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
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UniProt Comments for RFX2

Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function (). Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters (PubMed:10330134). Probably activates transcription of the testis-specific histone gene HIST1H1T ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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