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TR10A Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854720

MBS854720 is an antibody targeting TR10A. Also known as TR10A Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TR10A, Antibody
Full Product Name
TR10A Antibody
Product Gene Name
Product Synonym Names
Tumor necrosis factor receptor superfamily member 10A [Precursor]; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD261 antigen; TNFRSF10A; APO2; DR4; TRAILR1
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
TR10A antibody detects endogenous levels of total TR10A protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
50,089 Da
OMIM
603611
3D Structure
ModBase 3D Structure for O00220
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human TR10A.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TR10A antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-TR10A antibody
WB: 1:500-1:1000
ELISA: 1:1000

Western Blot (WB) of anti-TR10A antibody

Western blot analysis of extracts from K562 cells, COS-7 cells and RAW264.7 cells, using TR10A antibody.
Anti-TR10A Antibody – Cat# MBS854720

Product References and Citations for anti-TR10A antibody

Pan G., Science 276:111-113(1997). The MGC Project Team, Genome Res. 14:2121-2127(2004). Chaudhary P.M., Immunity 7:821-830(1997).

Other Notes

Small volumes of anti-TR10A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TR10A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 10A
NCBI Official Synonym Full Names
TNF receptor superfamily member 10a
NCBI Official Symbol
TNFRSF10A
NCBI Official Synonym Symbols
DR4; APO2; CD261; TRAILR1; TRAILR-1
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 10A
UniProt Synonym Protein Names
Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD_antigen: CD261
UniProt Gene Name
TNFRSF10A
UniProt Synonym Gene Names
APO2; DR4; TRAILR1; TRAIL receptor 1; TRAIL-R1
NCBI Protein Information
tumor necrosis factor receptor superfamily member 10A

NCBI Summary for TR10A

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
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UniProt Comments for TR10A

Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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