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RHG17 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854967

MBS854967 is an antibody targeting RHG17. Also known as RHG17 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RHG17, Antibody
Full Product Name
RHG17 Antibody
Product Gene Name
Product Synonym Names
NADRIN; neuron-associated developmentally regulated protein; RHG17; rho GTPase activating protein 17; RhoGAP interacting with CIP4 homologs 1; RICH1; RICH1B; WBP15
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
RHG17 antibody detects endogenous levels of total RHG17 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
42,512 Da
OMIM
608293
3D Structure
ModBase 3D Structure for Q68EM7
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human RHG17.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RHG17 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-RHG17 antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-RHG17 antibody

Western blot analysis of extracts from LOVO cells, using RHG17 antibody.
Anti-RHG17 Antibody – Cat# MBS854967

Product References and Citations for anti-RHG17 antibody

Richnau N., J. Biol. Chem. 276:35060-35070(2001). Ota T., Nat. Genet. 36:40-45(2004). The German cDNA consortium; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.

Other Notes

Small volumes of anti-RHG17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RHG17. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rho GTPase-activating protein 17 isoform 1
NCBI Official Synonym Full Names
Rho GTPase activating protein 17
NCBI Official Symbol
ARHGAP17
NCBI Official Synonym Symbols
PP367; RICH1; WBP15; MST066; MST110; NADRIN; PP4534; RICH-1; MSTP038; MSTP066; MSTP110
UniProt Protein Name
Rho GTPase-activating protein 17
UniProt Synonym Protein Names
Rho-type GTPase-activating protein 17; RhoGAP interacting with CIP4 homologs protein 1; RICH-1
UniProt Gene Name
ARHGAP17
UniProt Synonym Gene Names
RICH1; RICH-1
NCBI Protein Information
rho GTPase-activating protein 17

NCBI Summary for RHG17

RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA (MIM 165390), RAC1 (MIM 602048), and CDC42 (MIM 116952).[supplied by OMIM, Apr 2004]

UniProt Comments for RHG17

Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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