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Urocortin (UCN) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854970

MBS854970 is an antibody targeting UCN. Also known as Urocortin Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Urocortin (UCN), Antibody
Full Product Name
Urocortin Antibody
Product Gene Name
Product Synonym Names
UROTENSIN I
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
Urocortin antibody detects endogenous levels of total urocortin protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
13,458 Da
OMIM
600945
3D Structure
ModBase 3D Structure for P55089
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human urocortin.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-UCN antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-UCN antibody
IHC: 1:50-1:100
ELISA: 1:5000

Immunohistochemistry (IHC) of anti-UCN antibody

Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using urocortin antibody.
Anti-UCN Antibody – Cat# MBS854970

Product References and Citations for anti-UCN antibody

Kazumi Iino, J. Clin. Endocrinol. Metab., Nov 1997; 82: 3842-3850. Alison C. Holloway, Am J Physiol Endocrinol Metab, Jul 2002; 283: E165-E171. Toshio Nishikimi, Am J Physiol Heart Circ Physiol, Dec 2000; 279: 3031. Stacie C. Weninger, Endocrinology, Jan 2000; 141: 256.

Other Notes

Small volumes of anti-UCN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UCN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
urocortin preproprotein
NCBI Official Synonym Full Names
urocortin
NCBI Official Symbol
UCN
NCBI Official Synonym Symbols
UI; UROC
UniProt Protein Name
Urocortin
Protein Family
UniProt Gene Name
UCN
NCBI Protein Information
urocortin

NCBI Summary for UCN

This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family. The encoded preproprotein is proteolytically processed to generate the mature peptide, an endogenous ligand for both corticotropin-releasing factor receptor 1 and corticotropin-releasing factor receptor 2. In the brain this peptide may be responsible for the effects of stress on appetite. This peptide may also play a role in mood disorders, neurodegeneration, and skeletal system disorders. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin-2. [provided by RefSeq, Feb 2016]
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UniProt Comments for UCN

Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) (PubMed:8612563). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta (PubMed:8612563). Plays a role in the establishment of normal hearing thresholds (). Reduces food intake and regulates ghrelin levels in gastric body and plasma ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UCN antibody

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