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TIE1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854988

MBS854988 is an antibody targeting TIE1. Also known as TIE1 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TIE1, Antibody
Full Product Name
TIE1 Antibody
Product Gene Name
Product Synonym Names
TIE; Tyrosine-protein kinase receptor Tie-1 precursor
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
TIE1 antibody detects endogenous levels of total TIE1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
34,138 Da
OMIM
600222
3D Structure
ModBase 3D Structure for P35590
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human TIE1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TIE1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-TIE1 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Testing Data #2 of anti-TIE1 antibody

Western blot analysis of extracts from HepG2 cells, K562 cells and Jurkat cells, using TIE1 antibody.
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Anti-TIE1 Antibody – Cat# MBS854988

Product References and Citations for anti-TIE1 antibody

Partanen J., Mol. Cell. Biol. 12:1698-1707(1992). Partanen J.M., Submitted (JUL-1993) to the EMBL/GenBank/DDBJ databases. Zhang Z., Protein Sci. 13:2819-2824(2004).

Other Notes

Small volumes of anti-TIE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TIE1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tyrosine-protein kinase receptor Tie-1 isoform 1
NCBI Official Synonym Full Names
tyrosine kinase with immunoglobulin like and EGF like domains 1
NCBI Official Symbol
TIE1
NCBI Official Synonym Symbols
TIE; JTK14
UniProt Protein Name
Tyrosine-protein kinase receptor Tie-1
UniProt Gene Name
TIE1
UniProt Synonym Gene Names
TIE
NCBI Protein Information
tyrosine-protein kinase receptor Tie-1

NCBI Summary for TIE1

This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for TIE1

Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TIE1 antibody

 Reference Product  PubMed Publications
 TEK antibody  >13 publications with TIE1 and TEK
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