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Mevalonate Kinase (MVK) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855009

MBS855009 is an antibody targeting MVK. Also known as Mevalonate Kinase Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mevalonate Kinase (MVK), Antibody
Full Product Name
Mevalonate Kinase Antibody
Product Gene Name
Product Synonym Names
Mevalonate kinase; EC 2.7.1.36; MK
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
Mevalonate Kinase antibody detects endogenous levels of total Mevalonate Kinase protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
42,451 Da
OMIM
175900
3D Structure
ModBase 3D Structure for Q03426
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human Mevalonate Kinase.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MVK antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-MVK antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000

Testing Data of anti-MVK antibody

Peptide-+
Anti-MVK Antibody – Cat# MBS855009

Immunohistochemistry (IHC) of anti-MVK antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using Mevalonate Kinase antibody. Western blot analysis of extracts from COS-7 cells and COLO205 cells, using Mevalonate Kinase antibody.
Anti-MVK Antibody, Immunohistochemistry (IHC) – Cat# MBS855009

Product References and Citations for anti-MVK antibody

Schafer B.L., J. Biol. Chem. 267:13229-13238(1992). Graef E., Oncogene 9:81-87(1994). Houten S.M., Eur. J. Hum. Genet. 9:253-259(2001).

Other Notes

Small volumes of anti-MVK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MVK. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mevalonate kinase isoform a
NCBI Official Synonym Full Names
mevalonate kinase
NCBI Official Symbol
MVK
NCBI Official Synonym Symbols
MK; LRBP; MVLK; POROK3
UniProt Protein Name
Mevalonate kinase
Protein Family
UniProt Gene Name
MVK
UniProt Synonym Gene Names
MK
NCBI Protein Information
mevalonate kinase

NCBI Summary for MVK

This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
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UniProt Comments for MVK

May be a regulatory site in cholesterol biosynthetic pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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