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KCNJ2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855036

MBS855036 is an antibody targeting KCNJ2. Also known as KCNJ2 Antibody. Reactive in Human, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KCNJ2, Antibody
Full Product Name
KCNJ2 Antibody
Product Gene Name
Product Synonym Names
Inward rectifier potassium channel 2; Potassium channel; inwardly rectifying subfamily J member 2; Inward rectifier K(+) channel Kir2.1; Cardiac inward rectifier potassium channel; IRK1
Species Reactivity
Human, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
KCNJ2 antibody detects endogenous levels of total KCNJ2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
48,288 Da
OMIM
170390
3D Structure
ModBase 3D Structure for P63252
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human KCNJ2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KCNJ2 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-KCNJ2 antibody
IHC: 1:50-1:100
ELISA: 1:10000

Immunohistochemistry (IHC) of anti-KCNJ2 antibody

Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using KCNJ2 antibody.
Anti-KCNJ2 Antibody – Cat# MBS855036

Product References and Citations for anti-KCNJ2 antibody

Raab-Graham K.F., Report 5:2501-2505(1994). Tang W., Submitted (APR-1995) to the EMBL/GenBank/DDBJ databases. Wood L.S., Gene 163:313-317(1995).

Other Notes

Small volumes of anti-KCNJ2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNJ2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
inward rectifier potassium channel 2
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily J member 2
NCBI Official Symbol
KCNJ2
NCBI Official Synonym Symbols
IRK1; LQT7; SQT3; ATFB9; HHIRK1; KIR2.1; HHBIRK1
UniProt Protein Name
Inward rectifier potassium channel 2
UniProt Synonym Protein Names
Cardiac inward rectifier potassium channel; Inward rectifier K(+) channel Kir2.1; IRK-1; hIRK1; Potassium channel, inwardly rectifying subfamily J member 2
UniProt Gene Name
KCNJ2
UniProt Synonym Gene Names
IRK1; IRK-1; hIRK1
NCBI Protein Information
inward rectifier potassium channel 2

NCBI Summary for KCNJ2

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008]
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UniProt Comments for KCNJ2

Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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