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KCNV2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855078

MBS855078 is an antibody targeting KCNV2. Also known as KCNV2 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KCNV2, Antibody
Full Product Name
KCNV2 Antibody
Product Gene Name
anti-KCNV2 antibody
Product Synonym Names
KCNV2; potassium voltage-gated channel subfamily V member 2; voltage-gated potassium channel subunit Kv8.2
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
KCNV2 antibody detects endogenous levels of total KCNV2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
62,459 Da
OMIM
607604
3D Structure
ModBase 3D Structure for Q8TDN2
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human KCNV2.

Product Categories/Family for anti-KCNV2 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KCNV2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-KCNV2 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-KCNV2 antibody

Western blot analysis of extracts from MCF-7 cells, using KCNV2 antibody.
Anti-KCNV2 Antibody – Cat# MBS855078

Product References and Citations for anti-KCNV2 antibody

Ottschytsch N., Proc. Natl. Acad. Sci. U.S.A. 99:7986-7991(2002). Humphray S.J., Nature 429:369-374(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-KCNV2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNV2. It may not necessarily be applicable to this product.

NCBI GI #
19424136
NCBI GeneID
169522
NCBI Accession #
NP_598004.1
UniProt Primary Accession #
Q8TDN2
UniProt Secondary Accession #
Q5T6X0
UniProt Related Accession #
Q8TDN2
GenBank Nucleotide #
NM_133497.3
NCBI Official Full Name
potassium voltage-gated channel subfamily V member 2
NCBI Official Synonym Full Names
potassium voltage-gated channel modifier subfamily V member 2
NCBI Official Symbol
KCNV2
NCBI Official Synonym Symbols
Kv8.2; RCD3B; KV11.1
UniProt Protein Name
Potassium voltage-gated channel subfamily V member 2
UniProt Synonym Protein Names
Voltage-gated potassium channel subunit Kv8.2
Protein Family
Potassium voltage-gated channel subfamily
UniProt Gene Name
KCNV2
NCBI Protein Information
potassium voltage-gated channel subfamily V member 2

NCBI Summary for KCNV2

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008]
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UniProt Comments for KCNV2

Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.

Research Articles on KCNV2

1. Pharmacogenetic and case-control study evaluated the role of the variants of KCNA1, KCNA2, and KCNV2 in the susceptibility and drug resistance of genetic generalized epilepsies and revealed no significant association between 8 variants of KCNA1, KCNA2, and KCNV2 genes and risk or drug resistance of genetic generalized epilepsies after a Bonferroni correction for multiple comparisons.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KCNV2 antibody

 Reference Product  PubMed Publications
 KCNB1 antibody  >4 publications with KCNV2 and KCNB1
 KCNF1 antibody  >1 publications with KCNV2 and KCNF1

Pathways associated with anti-KCNV2 antibody

 Products by Pathway  Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Potassium Channels Pathway antibodies  Potassium Channels Pathway Diagram
 Voltage Gated Potassium Channels Pathway antibodies  Voltage Gated Potassium Channels Pathway Diagram

Diseases associated with anti-KCNV2 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >7 publications with KCNV2 and Congenital Abnormalities
 Heart Defects, Congenital Antibodies  >5 publications with KCNV2 and Heart Defects, Congenital
 Retinal Cone Dystrophy 3B Antibodies  >2 publications with KCNV2 and Retinal Cone Dystrophy 3B
 Seizures Antibodies  >1 publications with KCNV2 and Seizures
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