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GAD67 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855195

MBS855195 is an antibody targeting GAD67. Also known as GAD67 Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GAD67, Antibody
Full Product Name
GAD67 Antibody
Product Gene Name
Product Synonym Names
4.1.1.15; GLUTAMATE DECARBOXYLASE; BRAIN; 67-KD; glutamate decarboxylase 1 (brain; 67kD); lutamate decarboxylase 1 (brain; 67kDa); glutamate decarboxylase 1 isoform GAD25; glutamate decarboxylase 1 isoform GAD67
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
GAD67 antibody detects endogenous levels of total GAD67 protein.
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
47,440 Da
OMIM
603513
3D Structure
ModBase 3D Structure for Q99259
Immunogen
The antiserum was produced against synthesized peptide derived from human GAD67.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GAD67 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-GAD67 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000

Immunohistochemistry (IHC) of anti-GAD67 antibody

Peptide-+ Immunohistochemical analysis of paraffin-embedded human brain tissue using GAD67 antibody.
Anti-GAD67 Antibody – Cat# MBS855195

Western Blot (WB) of anti-GAD67 antibody

Western blot analysis of extracts from LOVO cells, using GAD67 antibody.
Anti-GAD67 Antibody, Western Blot (WB) – Cat# MBS855195

Product References and Citations for anti-GAD67 antibody

Jamil Kanaani, J. Biol. Chem., Dec 1999; 274: 37200. Susan M. Murphy, J. Histochem. Cytochem., Nov 1998; 46: 1261. M. Gierdalski, Cereb Cortex, Sep 2001; 11: 806-815. Kyung Soo Kim, Diabetes, Sep 2002; 51: 2764.

Other Notes

Small volumes of anti-GAD67 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GAD67. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glutamate decarboxylase 1 isoform GAD67
NCBI Official Synonym Full Names
glutamate decarboxylase 1
NCBI Official Symbol
GAD1
NCBI Official Synonym Symbols
GAD; SCP; CPSQ1
UniProt Protein Name
Glutamate decarboxylase 1
UniProt Synonym Protein Names
67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform
UniProt Gene Name
GAD1
UniProt Synonym Gene Names
GAD; GAD67; GAD-67
NCBI Protein Information
glutamate decarboxylase 1

NCBI Summary for GAD67

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
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UniProt Comments for GAD67

Catalyzes the production of GABA.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GAD67 antibody

 Reference Product  PubMed Publications
 GAD2 antibody  >40 publications with GAD67 and GAD2
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