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MTNR1A Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855199

MBS855199 is an antibody targeting MTNR1A. Also known as MTNR1A Antibody. Reactive in Human, Mouse, Rat. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MTNR1A, Antibody
Full Product Name
MTNR1A Antibody
Product Gene Name
anti-MTNR1A antibody
Product Synonym Names
Melatonin receptor type 1A; Mel-1A-R; Mel1a melatonin receptor; MTNR1A
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
MTR1A antibody detects endogenous levels of total MTR1A protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
39,375 Da
OMIM
600665
3D Structure
ModBase 3D Structure for P48039
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human MTR1A.

Product Categories/Family for anti-MTNR1A antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MTNR1A antibody
Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-MTNR1A antibody
IF: 1:100-1:500
ELISA: 1:5000

Immunofluorescence (IF) of anti-MTNR1A antibody

Peptide-+ Immunofluorescence analysis of HepG2 cells, using MTR1A antibody.
Anti-MTNR1A Antibody – Cat# MBS855199

Product References and Citations for anti-MTNR1A antibody

Reppert S.M., Neuron 13:1177-1185(1994). Ebisawa T., Biochem. Biophys. Res. Commun. 262:832-837(1999). The MGC Project Team, Genome Res. 14:2121-2127(2004).

Other Notes

Small volumes of anti-MTNR1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MTNR1A. It may not necessarily be applicable to this product.

NCBI GI #
5174593
NCBI GeneID
4543
NCBI Accession #
NP_005949.1
UniProt Primary Accession #
P48039
UniProt Secondary Accession #
A0AVC5; B0M0L2
UniProt Related Accession #
P48039
GenBank Nucleotide #
NM_005958.4
NCBI Official Full Name
melatonin receptor type 1A
NCBI Official Synonym Full Names
melatonin receptor 1A
NCBI Official Symbol
MTNR1A
NCBI Official Synonym Symbols
MT1; MEL-1A-R
UniProt Protein Name
Melatonin receptor type 1A
Protein Family
Melatonin receptor
UniProt Gene Name
MTNR1A
UniProt Synonym Gene Names
Mel-1A-R; Mel1a receptor
NCBI Protein Information
melatonin receptor type 1A

NCBI Summary for MTNR1A

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]
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UniProt Comments for MTNR1A

High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Research Articles on MTNR1A

1. There were no statistically significant differences in the distribution of MTNR1A rs2119882 and MTNR1B rs4753426 genotypes and alleles between women with gestational diabetes and healthy pregnant women.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MTNR1A antibody

 Reference Product  PubMed Publications
 MTNR1B antibody  >21 publications with MTNR1A and MTNR1B
 GPR50 antibody  >4 publications with MTNR1A and GPR50

Pathways associated with anti-MTNR1A antibody

 Products by Pathway  Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-MTNR1A antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with MTNR1A and Neoplasms
 Drug Toxicity Antibodies  >2 publications with MTNR1A and Drug Toxicity
 Child Development Disorders, Pervasive Antibodies  >2 publications with MTNR1A and Child Development Disorders, Pervasive
 Insulin Resistance Antibodies  >1 publications with MTNR1A and Insulin Resistance
 Diabetes Mellitus Antibodies  >1 publications with MTNR1A and Diabetes Mellitus
 Movement Disorders Antibodies  >1 publications with MTNR1A and Movement Disorders
 Brain Diseases Antibodies  >1 publications with MTNR1A and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with MTNR1A and Kidney Diseases

Organs/Tissues associated with anti-MTNR1A antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with MTNR1A and Liver
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