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Septin 4 (SEPT4) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855208

Rabbit polyclonal SEPT4 (1) antibody was raised against a 14 amino acid peptide from the C terminal residues of human SEPT4 protein. More details

$430 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
septin 4 (SEPT4), Polyclonal Antibody
Full Product Name
septin 4 Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Lyophilized anti-SEPT4 antibody purified by protein A column containing 0.02% NaN3
Preparation and Storage
The Lyophilized antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Molecular Weight
30,809 Da
OMIM
603696
3D Structure
ModBase 3D Structure for O43236
Reconstitution
Reconstitute in 200ul sterile H2O.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SEPT4 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-SEPT4 antibody
Peptide ELISA: 1:80,000
WB: 1:200-500.

Testing Data of anti-SEPT4 antibody

Rabbit Anti-SEPT4 Polyclonal Antibody – Cat# MBS855208

Product References and Citations for anti-SEPT4 antibody

(1) Tanaka M., Tanaka T., Kijima H., Itoh J., Matsuda T., Hori S., Yamamoto M. Characterization of tissue-and cell-type-specific expression of a novel human septin family gene, Bradeion. Biochem Biophys Res Commun. 2001; 286(3):547-53.

Other Notes

Small volumes of anti-SEPT4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEPT4 purchase

MBS855208 is an antibody targeting SEPT4. Also known as septin 4 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SEPT4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
septin-4 isoform 1
NCBI Official Synonym Full Names
septin 4
NCBI Official Symbol
SEPT4
NCBI Official Synonym Symbols
H5; ARTS; MART; SEP4; CE5B3; PNUTL2; hucep-7; BRADEION; hCDCREL-2
UniProt Protein Name
Septin-4
UniProt Synonym Protein Names
Apoptosis-related protein in the TGF-beta signaling pathway; ARTS; Bradeion beta; Brain protein H5; CE5B3 beta; Cell division control-related protein 2; hCDCREL-2; Cerebral protein 7; Peanut-like protein 2
Protein Family
UniProt Gene Name
SEPT4
UniProt Synonym Gene Names
ARTS; PNUTL2; SEP4; ARTS; hCDCREL-2
NCBI Protein Information
septin-4

NCBI Summary for SEPT4

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. [provided by RefSeq, Nov 2010]
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UniProt Comments for SEPT4

Filament-forming cytoskeletal GTPase (). May play a role in cytokinesis (Potential). Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SEPT4 antibody

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