• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CDK11 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS855235

MBS855235 is an antibody targeting CDK11. Also known as CDK11 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDK11, Antibody
Full Product Name
CDK11 Antibody
Product Gene Name
Product Synonym Names
Cyclin-dependent kinase 11A; EC=2.7.11.22; Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase CDC2L2
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CDK11 antibody detects endogenous levels of total CDK11 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
49,624 Da
OMIM
116951
3D Structure
ModBase 3D Structure for Q9UQ88
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CDK11.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CDK11 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CDK11 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-CDK11 antibody

Western blot analysis of extracts from HUVEC cells, HepG2 cells and CoLo cells, using CDK11 antibody.
Anti-CDK11 Antibody – Cat# MBS855235

Product References and Citations for anti-CDK11 antibody

Xiang J., J. Biol. Chem. 269:15786-15794(1994) [PubMed: 8195233]. Gururajan R., Genome Res. 8:929-939(1998) [PubMed: 9750192]. Gregory S.G., Nature 441:315-321(2006) [PubMed: 16710414]. Gururajan R., Genome Res. 8:929-939(1998) [PubMed: 9750192]. Gregory S.G., Nature 441:315-321(2006) [PubMed: 16710414].

Other Notes

Small volumes of anti-CDK11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cyclin-dependent kinase 11A isoform 5
NCBI Official Synonym Full Names
cyclin dependent kinase 11A
NCBI Official Symbol
CDK11A
NCBI Official Synonym Symbols
CDC2L2; CDC2L3; p58GTA; PITSLRE; CDK11-p46; CDK11-p58; CDK11-p110
UniProt Protein Name
Cyclin-dependent kinase 11A
UniProt Synonym Protein Names
Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase CDC2L2
UniProt Gene Name
CDK11A
UniProt Synonym Gene Names
CDC2L2; CDC2L3; PITSLREB
NCBI Protein Information
cyclin-dependent kinase 11A

NCBI Summary for CDK11

This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Show more

UniProt Comments for CDK11

Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.

Research Articles on CDK11

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000